Phase I study of temozolomide in paediatric patients with advanced cancer. United Kingdom Children's Cancer Study Group.

Phase I study of temozolomide in paediatric patients with advanced cancer. United Kingdom Children's Cancer Study Group.

A phase I study of temozolomide administered orally once a day, on 5 consecutive days, between 500 and 1200 mg m(-2) per 28-day cycle was performed. Children were stratified according to prior craniospinal irradiation or nitrosourea therapy. Sixteen of 20 patients who had not received prior craniosp...

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Bibliographic Details
Main Authors: Estlin, E. J., Lashford, L., Ablett, S., Price, L., Gowing, R., Gholkar, A., Kohler, J., Lewis, I. J., Morland, B., Pinkerton, C. R., Stevens, M. C., Mott, M., Stevens, R., Newell, D. R., Walker, D., Dicks-Mireaux, C., McDowell, H., Reidenberg, P., Statkevich, P., Marco, A., Batra, V., Dugan, M., Pearson, A. D.
Format: Online
Language:English
Published: Nature Publishing Group|1 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063055/

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