Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines
Temozolomide (TMZ) is the standard chemotherapeutic agent for human malignant glioma, but intrinsic or acquired chemoresistance represents a major obstacle to successful treatment of this highly lethal group of tumours. Obtaining better understanding of the molecular mechanisms underlying TMZ resist...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Springer US
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273683/ |