Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

Temozolomide (TMZ) is the standard chemotherapeutic agent for human malignant glioma, but intrinsic or acquired chemoresistance represents a major obstacle to successful treatment of this highly lethal group of tumours. Obtaining better understanding of the molecular mechanisms underlying TMZ resist...

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Bibliographic Details
Main Authors: Sun, Stella, Wong, T. S., Zhang, X. Q., Pu, Jenny K. S., Lee, Nikki P., Day, Philip J. R., Ng, Gloria K. B., Lui, W. M., Leung, Gilberto K. K.
Format: Online
Language:English
Published: Springer US 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273683/