erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification.
Amplification and overexpression of the erbB-2 oncogene is an unfavourable prognostic marker in human breast cancer and occurs in approximately 25% of breast carcinomas. We used erbB-2 antisense oligonucleotides to inhibit the proliferation of human breast cancer cell lines. erbB-2 antisense oligonu...
Main Authors: | Colomer, R., Lupu, R., Bacus, S. S., Gelmann, E. P. |
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Format: | Online |
Language: | English |
Published: |
1994
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033560/ |
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