erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification.

Amplification and overexpression of the erbB-2 oncogene is an unfavourable prognostic marker in human breast cancer and occurs in approximately 25% of breast carcinomas. We used erbB-2 antisense oligonucleotides to inhibit the proliferation of human breast cancer cell lines. erbB-2 antisense oligonu...

Full description

Bibliographic Details
Main Authors: Colomer, R., Lupu, R., Bacus, S. S., Gelmann, E. P.
Format: Online
Language:English
Published: 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033560/