6-Thioguanine: Antimitotic Effect on Human Lymphocytes in vitro Prevented by Adenine

The action of 6-thioguanine on the division of PHA-stimulated human lymphocytes in vitro has been investigated and shown to have a definite antimitotic effect which is prevented by adenine but not by guanine or hypoxanthine. It is suggested that in this test system 6-TG exerts its main inhibitory ac...

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Bibliographic Details
Main Authors: Price, D. J., Timson, J.
Format: Online
Language:English
Published: 1971
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008542/