A phase I study of regional 5-fluorouracil and systemic folinic acid for patients with colorectal liver metastases.

A phase I study of regional 5-fluorouracil and systemic folinic acid for patients with colorectal liver metastases.

A phase I study was undertaken in order to establish the maximum tolerated dose of intra-hepatic arterial 5-fluorouracil (5-FU) when given in combination with systemic folinic acid. Patients with colorectal liver metastases (n = 10) received escalating doses of 5-FU as a 24 h infusion with a fixed d...

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Bibliographic Details
Main Authors:	Anderson, J. H., Kerr, D. J., Cooke, T. G., McArdle, C. S.
Format:	Online
Language:	English
Published:	1992
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977775/

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