High-dose folinic acid and 5-fluorouracil bolus and continuous infusion in advanced colorectal cancer: poor response rate in unselected patients.
We have conducted a retrospective study of high-dose folinic acid and 5-fluorouracil in 96 patients with advanced colorectal cancer. Patients received 200 mg m-2 (maximum 300-350 mg) folinic acid by infusion over 2 h followed by an i.v. bolus of 5-fluorouracil 400 mg m-2 then an infusion of 5-fluoro...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033907/ |