A pharmacokinetic comparison of intravenous versus intra-arterial folinic acid.

Recent clinical trials have suggested that a combination of folinic acid and 5-fluorouracil (5-FU) may improve response rates and survival in patients with advanced colorectal cancer. However, this regimen has been complicated by potentially life threatening toxicity. Regional delivery of folinic ac...

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Bibliographic Details
Main Authors: Anderson, J. H., Kerr, D. J., Setanoians, A., Cooke, T. G., McArdle, C. S.
Format: Online
Language:English
Published: 1992
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977354/