Effects of cyclosporin A and a non-immunosuppressive analogue, O-acetyl cyclosporin A, upon the growth of parent and multidrug resistant human lung cancer cells in vitro.
We have studied the ability of cyclosporin A (CsA) and a non-immunosuppressive analogue, O-acetyl cyclosporin A (OACsA, B3-243) to inhibit the growth of human lung cancer cells in vitro. Using continuous drug exposure and the MTT colorimetric assay to determine cell growth we found that CsA produced...
Main Authors: | Twentyman, P. R., Wright, K. A., Wallace, H. M. |
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Format: | Online |
Language: | English |
Published: |
1992
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977618/ |
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