Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
In this report we have approached two questions relating to the mechanism of action of cyclosporin A (CsA). First, we address whether the major cytosolic protein for CsA, cyclophilin, is directly involved in mediating the immunosuppressive activity of this drug, and, in particular, whether inhibitio...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1991
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118809/ |