Involvement of basic fibroblast growth factor in suramin-induced inhibition of V79/AP4 fibroblast cell proliferation.
The V79/AP4 Chinese hamster fibroblasts were densely stained with the anti-basic fibroblast growth factor (bFGF) antibody demonstrating an endogenous production of the peptide. The in vitro proliferation of these cells was stimulated by exogenous bFGF and the maximum growth (259% increase in 3H-thym...
Main Authors: | Bernardini, N., Giannessi, F., Bianchi, F., Dolfi, A., Lupetti, M., Citti, L., Danesi, R., Del Tacca, M. |
---|---|
Format: | Online |
Language: | English |
Published: |
1993
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968483/ |
Similar Items
-
Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane.
by: Danesi, R., et al.
Published: (1993) -
Suramin prevents neovascularisation and tumour growth through blocking of basic fibroblast growth factor activity.
by: Pesenti, E., et al.
Published: (1992) -
A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanions.
by: Braddock, P. S., et al.
Published: (1994) -
The effect of suramin on inhibiting fibroblast proliferation and preventing epidural fibrosis after laminectomy in rats
by: Dai, Jihang, et al.
Published: (2016) -
Modification of the volumetric growth responses and steady-state hypoxic fractions of xenografted DLD-2 human colon carcinomas by administration of basic fibroblast growth factor or suramin.
by: Leith, J. T., et al.
Published: (1992)