Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation

Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation

Simian Virus 40 (SV40) large T antigen (T Ag) is a multifunctional viral oncoprotein that regulates viral and cellular transcriptional activity. However, the mechanisms by which such regulation occurs remain unclear. Here we show that T antigen represses CBP-mediated transcriptional activity. This r...

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Bibliographic Details
Main Authors:	Valls, Ester, Blanco-García, Noemí, Aquizu, Naiara, Piedra, David, Estarás, Conchi, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Format:	Online
Language:	English
Published:	Oxford University Press 2007
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874590/

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