Simian virus 40 (SV40)-transgenic mice that develop tumors are specifically tolerant to SV40 T antigen

The ability to mount an immune response to simian virus 40 (SV40) T antigen was evaluated using mice from two distinct SV40 transgenic lines derived from injection of the same gene construct. Our studies demonstrate functional immune tolerance to SV40 T antigen in a SV40 transgenic line that consist...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188506/