Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation
Simian Virus 40 (SV40) large T antigen (T Ag) is a multifunctional viral oncoprotein that regulates viral and cellular transcriptional activity. However, the mechanisms by which such regulation occurs remain unclear. Here we show that T antigen represses CBP-mediated transcriptional activity. This r...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2007
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874590/ |