Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions

Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions

The simultaneous testing of a large number of hypotheses in a genome scan, using individual thresholds for significance, inherently leads to inflated genome-wide false positive rates. There exist various approaches to approximating the correct genomewide p-values under various assumptions, either by...

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Bibliographic Details
Main Authors:	Sinha, Ritwik, Sinha, Moumita, Mathew, George, Elston, Robert C, Luo, Yuqun
Format:	Online
Language:	English
Published:	BioMed Central 2005
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866763/

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