Power and type I error rate of false discovery rate approaches in genome-wide association studies

In genome-wide genetic studies with a large number of markers, balancing the type I error rate and power is a challenging issue. Recently proposed false discovery rate (FDR) approaches are promising solutions to this problem. Using the 100 simulated datasets of a genome-wide marker map spaced about...

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Bibliographic Details
Main Authors: Yang, Qiong, Cui, Jing, Chazaro, Irmarie, Cupples, L Adrienne, Demissie, Serkalem
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866802/