Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions
The simultaneous testing of a large number of hypotheses in a genome scan, using individual thresholds for significance, inherently leads to inflated genome-wide false positive rates. There exist various approaches to approximating the correct genomewide p-values under various assumptions, either by...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866763/ |