HIV-1 Subtype B Protease and Reverse Transcriptase Amino Acid Covariation
Despite the high degree of HIV-1 protease and reverse transcriptase (RT) mutation in the setting of antiretroviral therapy, the spectrum of possible virus variants appears to be limited by patterns of amino acid covariation. We analyzed patterns of amino acid covariation in protease and RT sequences...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866358/ |