HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

HIV-1 protease (PR), reverse transcriptase (RT), and integrase (IN) variability presents a challenge to laboratories performing genotypic resistance testing. This challenge will grow with increased sequencing of samples enriched for proviral DNA such as dried blood spots and increased use of next-ge...

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Bibliographic Details
Main Authors: Rhee, Soo-Yon, Sankaran, Kris, Varghese, Vici, Winters, Mark A., Hurt, Christopher B., Eron, Joseph J., Parkin, Neil, Holmes, Susan P., Holodniy, Mark, Shafer, Robert W.
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907232/