HIV-1 Protease and Reverse Transcriptase Control the Architecture of Their Nucleocapsid Partner

The HIV-1 nucleocapsid is formed during protease (PR)-directed viral maturation, and is transformed into pre-integration complexes following reverse transcription in the cytoplasm of the infected cell. Here, we report a detailed transmission electron microscopy analysis of the impact of HIV-1 PR and...

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Bibliographic Details
Main Authors: Mirambeau, Gilles, Lyonnais, Sébastien, Coulaud, Dominique, Hameau, Laurence, Lafosse, Sophie, Jeusset, Josette, Borde, Isabelle, Reboud-Ravaux, Michèle, Restle, Tobias, Gorelick, Robert J., Le Cam, Eric
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940317/