Cell-based expression cloning for identification of polypeptides that hypersensitize mammalian cells to mitotic arrest
Microtubule inhibitors such as Vinblastine and Paclitaxel are chemotherapy agents that activate the mitotic spindle checkpoint, arresting cells in mitosis and leading to cell death. The pathways that connect mitotic arrest to cell death are not well characterized. We developed a mammalian cell-based...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Biological Procedures Online
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1455480/ |