Myricetin Inhibits Islet Amyloid Polypeptide (IAPP) Aggregation and Rescues Living Mammalian Cells from IAPP Toxicity
The aggregation of the amyloidogenic polypeptide IAPP (Islet Amyloid Polypeptide, amylin) is believed to play a direct role in the death of pancreatic β-islet cells in type II diabetes. Preventing the initial aggregation event of IAPP is one strategy for slowing, and possibly preventing, the progres...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Bentham Open
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394101/ |