Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase
In yeast, the Mad2 protein is required for the M phase arrest induced by microtubule inhibitors, but the protein is not essential under normal culture conditions. We tested whether the Mad2 protein participates in regulating the timing of anaphase onset in mammalian cells in the absence of microtubu...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1998
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137176/ |