Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs
As part of an effort to develop stable and replicable unnatural base pairs, we have evaluated a large number of unnatural nucleotides with predominantly hydrophobic nucleobases. Despite its limited aromatic surface area, a nucleobase analog scaffold that has emerged as being especially promising is...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440882/ |