Molecular Identification of a Malaria Merozoite Surface Sheddase
Proteolytic shedding of surface proteins during invasion by apicomplexan parasites is a widespread phenomenon, thought to represent a mechanism by which the parasites disengage adhesin-receptor complexes in order to gain entry into their host cell. Erythrocyte invasion by merozoites of the malaria p...
Main Authors: | Harris, Philippa K, Yeoh, Sharon, Dluzewski, Anton R, O'Donnell, Rebecca A, Withers-Martinez, Chrislaine, Hackett, Fiona, Bannister, Lawrence H, Mitchell, Graham H, Blackman, Michael J |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2005
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291349/ |
Similar Items
-
Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress
by: Collins, Christine R., et al.
Published: (2013) -
Immunization against a merozoite sheddase promotes multiple invasion of red blood cells and attenuates Plasmodium infection in mice
by: Smith, Ryan C, et al.
Published: (2014) -
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite
by: O'Donnell, Rebecca A., et al.
Published: (2006) -
Phosphatidylserine exposure is required for ADAM17 sheddase function
by: Sommer, Anselm, et al.
Published: (2016) -
Proteolytic Activation of the Essential Parasitophorous Vacuole Cysteine Protease SERA6 Accompanies Malaria Parasite Egress from Its Host Erythrocyte*
by: Ruecker, Andrea, et al.
Published: (2012)