Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

Release of the malaria merozoite from its host erythrocyte (egress) and invasion of a fresh cell are crucial steps in the life cycle of the malaria pathogen. Subtilisin-like protease 1 (SUB1) is a parasite serine protease implicated in both processes. In the most dangerous human malarial species, Pl...

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Bibliographic Details
Main Authors: Withers-Martinez, Chrislaine, Suarez, Catherine, Fulle, Simone, Kher, Samir, Penzo, Maria, Ebejer, Jean-Paul, Koussis, Kostas, Hackett, Fiona, Jirgensons, Aigars, Finn, Paul, Blackman, Michael J.
Format: Online
Language:English
Published: Elsevier Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378952/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378952/

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