Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

Abstract Background Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes blood stage-derived Plasmodium berghei schizonts that have been purif...

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Bibliographic Details
Main Authors: Gesine Kaiser, Mariana De Niz, Paul-Christian Burda, Livia Niklaus, Rebecca Limenitakis Stanway, Volker Heussler
Format: Article
Language:English
Published: BioMed Central 2017-08-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-017-1949-y