Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase

Maintenance of telomere integrity requires the dynamic interplay between telomerase, telomere-associated proteins and DNA repair proteins. These interactions are vital to suppress DNA damage responses and changes in chromosome dynamics that can result in aneuploidy or other transforming aberrations....

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Bibliographic Details
Main Authors: Ting, Nicholas S. Y., Yu, Yaping, Pohorelic, Brant, Lees-Miller, Susan P., Beattie, Tara L.
Format: Online
Language:English
Published: Oxford University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1075923/