Tandem oligonucleotide synthesis using linker phosphoramidites
Multiple oligonucleotides of the same or different sequence, linked end-to-end in tandem can be synthesized in a single automated synthesis. A linker phosphoramidite [R. T. Pon and S. Yu (2004) Nucleic Acids Res., 32, 623–631] is added to the 5′-terminal OH end of a support-bound oligonucleotide to...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074720/ |