Proline-based Phosphoramidite Reagents for the Reductive Ligation of S-Nitrosothiols
S-Nitrosothiols have many biological implications but are rarely used in organic synthesis. In this work we report the development of proline-based phosphoramidite substrates that can effectively convert S-nitrosothiols to proline-based sulfenamides through a reductive ligation process. A unique pro...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848125/ |