Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite

Guanine (G)-rich sequences can form a noncanonical four-stranded structure known as the G-quadruplex. G-quadruplex structures are interesting because of their potential biological properties and use in nanosciences. Here, we describe a method to prepare highly stable G-quadruplexes by linking four G...

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Bibliographic Details
Main Authors: Ferreira, Rubén, Alvira, Margarita, Aviñó, Anna, Gómez-Pinto, Irene, González, Carlos, Gabelica, Valérie, Eritja, Ramon
Format: Online
Language:English
Published: WILEY-VCH Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922461/