Levels of ADAM10 are reduced in Alzheimer’s disease CSF
Abstract Background The disintegrin metalloproteinase 10 (ADAM10) is the main α-secretase acting in the non-amyloidogenic processing of the amyloid precursor protein. This study assesses whether ADAM10 is present in cerebrospinal fluid (CSF), and whether it has potential as a biomarker for Alzheimer...
Main Authors: | Aitana Sogorb-Esteve, María-Salud García-Ayllón, Johan Gobom, Jordi Alom, Henrik Zetterberg, Kaj Blennow, Javier Sáez-Valero |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2018-07-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1255-9 |
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