Levels of ADAM10 are reduced in Alzheimer’s disease CSF

Levels of ADAM10 are reduced in Alzheimer’s disease CSF

Abstract Background The disintegrin metalloproteinase 10 (ADAM10) is the main α-secretase acting in the non-amyloidogenic processing of the amyloid precursor protein. This study assesses whether ADAM10 is present in cerebrospinal fluid (CSF), and whether it has potential as a biomarker for Alzheimer...

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Bibliographic Details
Main Authors: Aitana Sogorb-Esteve, María-Salud García-Ayllón, Johan Gobom, Jordi Alom, Henrik Zetterberg, Kaj Blennow, Javier Sáez-Valero
Format: Article
Language:English
Published: BioMed Central 2018-07-01
Series:Journal of Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1255-9

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http://link.springer.com/article/10.1186/s12974-018-1255-9

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