Targeting metabotropic glutamate receptors for novel treatments of schizophrenia
Abstract Support for the N-methyl-d-aspartate receptor (NMDAR) hypofunction hypothesis of schizophrenia has led to increasing focus on restoring proper glutamatergic signaling as an approach for treatment of this devastating disease. The ability of metabotropic glutamate (mGlu) receptors to modulate...
Main Authors: | James Maksymetz, Sean P. Moran, P. Jeffrey Conn |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2017-04-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-017-0293-z |
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