Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis
Abstract Background Although assemblies of hydrophobic-modified bacitracin A with PLGA (Nano-BAPLGA) have demonstrated promising antibacterial activities against both Gram-positive and Gram-negative bacteria, the desirable antibacterial potency has remained challenging due to the low solubility of N...
Main Authors: | Wei Hong, Lipeng Liu, Yining Zhao, Yinghui Liu, Dexian Zhang, Mingchun Liu |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2018-09-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12951-018-0397-3 |
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