Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

by Gutierrez-Achury, Javier, Zhernakova, Alexandra, Pulit, Sara L., Trynka, Gosia, Hunt, Karen A., Romanos, Jihane, Raychaudhuri, Soumya, van Heel, David A., Wijmenga, Cisca, de Bakker, Paul I.W.
Published 2015

Exome Sequencing of 75 Individuals from Multiply Affected Coeliac Families and Large Scale Resequencing Follow Up

by Mistry, Vanisha, Bockett, Nicholas A., Levine, Adam P., Mirza, Muddassar M., Hunt, Karen A., Ciclitira, Paul J., Hummerich, Holger, Neuhausen, Susan L., Simpson, Michael A., Plagnol, Vincent, van Heel, David A.
Published 2015

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

by Ludvigsson, Jonas F., Bai, Julio C., Biagi, Federico, Card, Timothy R., Ciacci, Carolina, Ciclitira, Paul J., Green, Peter H.R., Hadjivassiliou, Marios, Holdoway, Anne, van Heel, David A, Kaukinen, Katri, Leffler, Daniel A, Leonard, Jonathan N, Lundin, Knut E.A., McGough, Norma, Davidson, Mike, Murray, Joseph A., Swift, Gillian L., Zingone, Fabiana, Walker, Marjorie M., Sanders, David S
Published 2014

Pervasive Sharing of Genetic Effects in Autoimmune Disease

by Cotsapas, Chris, Voight, Benjamin F., Rossin, Elizabeth, Lage, Kasper, Neale, Benjamin M., Wallace, Chris, Abecasis, Gonçalo R., Barrett, Jeffrey C., Behrens, Timothy, Cho, Judy, De Jager, Philip L., Elder, James T., Graham, Robert R., Gregersen, Peter, Klareskog, Lars, Siminovitch, Katherine A., van Heel, David A., Wijmenga, Cisca, Worthington, Jane, Todd, John A., Hafler, David A., Rich, Stephen S., Daly, Mark J.
Published 2011

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

by Romanos, Jihane, Rosén, Anna, Kumar, Vinod, Trynka, Gosia, Franke, Lude, Szperl, Agata, Gutierrez-Achury, Javier, van Diemen, Cleo C, Kanninga, Roan, Jankipersadsing, Soesma A, Steck, Andrea, Eisenbarth, Georges, van Heel, David A, Cukrowska, Bozena, Bruno, Valentina, Mazzilli, Maria Cristina, Núñez, Concepcion, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Rewers, Marian, Norris, Jill M, Ivarsson, Anneli, Boezen, H Marieke, Liu, Edwin, Wijmenga, Cisca
Published 2014

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

by Ludvigsson, Jonas F, Bai, Julio C, Biagi, Federico, Card, Timothy R, Ciacci, Carolina, Ciclitira, Paul J, Green, Peter H R, Hadjivassiliou, Marios, Holdoway, Anne, van Heel, David A, Kaukinen, Katri, Leffler, Daniel A, Leonard, Jonathan N, Lundin, Knut E A, McGough, Norma, Davidson, Mike, Murray, Joseph A, Swift, Gillian L, Walker, Marjorie M, Zingone, Fabiana, Sanders, David S
Published 2014

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

by Fehrmann, Rudolf S. N., Jansen, Ritsert C., Veldink, Jan H., Westra, Harm-Jan, Arends, Danny, Bonder, Marc Jan, Fu, Jingyuan, Deelen, Patrick, Groen, Harry J. M., Smolonska, Asia, Weersma, Rinse K., Hofstra, Robert M. W., Buurman, Wim A., Rensen, Sander, Wolfs, Marcel G. M., Platteel, Mathieu, Zhernakova, Alexandra, Elbers, Clara C., Festen, Eleanora M., Trynka, Gosia, Hofker, Marten H., Saris, Christiaan G. J., Ophoff, Roel A., van den Berg, Leonard H., van Heel, David A., Wijmenga, Cisca, te Meerman, Gerard J., Franke, Lude
Published 2011

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

by Hunt, Karen A, Mistry, Vanisha, Bockett, Nicholas A, Ahmad, Tariq, Ban, Maria, Barker, Jonathan N, Barrett, Jeffrey C, Blackburn, Hannah, Brand, Oliver, Burren, Oliver, Capon, Francesca, Compston, Alastair, Gough, Stephen CL, Jostins, Luke, Kong, Yong, Lee, James C, Lek, Monkol, MacArthur, Daniel G, Mansfield, John C, Mathew, Christopher G, Mein, Charles A, Mirza, Muddassar, Nutland, Sarah, Onengut-Gumuscu, Suna, Papouli, Efterpi, Parkes, Miles, Rich, Stephen S., Sawcer, Steven, Satsangi, Jack, Simmonds, Matthew J, Trembath, Richard C, Walker, Neil M, Wozniak, Eva, Todd, John A, Simpson, Michael A, Plagnol, Vincent, van Heel, David A
Published 2013

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

by Lenz, Tobias L., Deutsch, Aaron J., Han, Buhm, Hu, Xinli, Okada, Yukinori, Eyre, Stephen, Knapp, Michael, Zhernakova, Alexandra, Huizinga, Tom W.J., Abecasis, Goncalo, Becker, Jessica, Boeckxstaens, Guy E., Chen, Wei-Min, Franke, Andre, Gladman, Dafna D., Gockel, Ines, Gutierrez-Achury, Javier, Martin, Javier, Nair, Rajan P., Nöthen, Markus M., Onengut-Gumuscu, Suna, Rahman, Proton, Rantapää-Dahlqvist, Solbritt, Stuart, Philip E., Tsoi, Lam C., Van Heel, David A., Worthington, Jane, Wouters, Mira M., Klareskog, Lars, Elder, James T., Gregersen, Peter K., Schumacher, Johannes, Rich, Stephen S., Wijmenga, Cisca, Sunyaev, Shamil R., de Bakker, Paul I.W., Raychaudhuri, Soumya
Published 2015

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

by Trynka, Gosia, Hunt, Karen A, Bockett, Nicholas A, Romanos, Jihane, Mistry, Vanisha, Szperl, Agata, Bakker, Sjoerd F, Bardella, Maria Teresa, Bhaw-Rosun, Leena, Castillejo, Gemma, de la Concha, Emilio G., de Almeida, Rodrigo Coutinho, Dias, Kerith-Rae M, van Diemen, Cleo C., Dubois, Patrick CA, Duerr, Richard H., Edkins, Sarah, Franke, Lude, Fransen, Karin, Gutierrez, Javier, Heap, Graham AR, Hrdlickova, Barbara, Hunt, Sarah, Izurieta, Leticia Plaza, Izzo, Valentina, Joosten, Leo AB, Langford, Cordelia, Mazzilli, Maria Cristina, Mein, Charles A, Midah, Vandana, Mitrovic, Mitja, Mora, Barbara, Morelli, Marinita, Nutland, Sarah, Núñez, Concepción, Onengut-Gumuscu, Suna, Pearce, Kerra, Platteel, Mathieu, Polanco, Isabel, Potter, Simon, Ribes-Koninckx, Carmen, Ricaño-Ponce, Isis, Rich, Stephen S., Rybak, Anna, Santiago, José Luis, Senapati, Sabyasachi, Sood, Ajit, Szajewska, Hania, Troncone, Riccardo, Varadé, Jezabel, Wallace, Chris, Wolters, Victorien M, Zhernakova, Alexandra, Thelma, B.K., Cukrowska, Bozena, Urcelay, Elena, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Barrett, Jeffrey C, Plagnol, Vincent, Deloukas, Panos, Wijmenga, Cisca, van Heel, David A
Published 2011

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

by Prins, Bram. P., Abbasi, Ali, Wong, Anson, Vaez, Ahmad, Nolte, Ilja, Franceschini, Nora, Stuart, Philip E., Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P., Valdes, Ana M., Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D., Tsoi, Lam C., Evangelou, Evangelos, Nair, Rajan P., Grant, Struan F. A., Polychronakos, Constantin, Radstake, Timothy R. D., van Heel, David A., Dunstan, Melanie L., Wood, Nicholas W., Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Markus, Hugh S., Elder, James T., Knight, Jo, Arking, Dan E., Spector, Timothy D., Koeleman, Bobby P. C., van Duijn, Cornelia M., Martin, Javier, Morris, Andrew P., Weersma, Rinse K., Wijmenga, Cisca, Munroe, Patricia B., Perry, John R. B., Pouget, Jennie G., Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z.
Published 2016