TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis

by Tejasvi, Trilokraj, Stuart, Philip E., Chandran, Vinod, Voorhees, John J., Gladman, Dafna D., Rahman, Proton, Elder, James T., Nair, Rajan P.
Published 2011

Heterogeneity of Inflammatory and Cytokine Networks in Chronic Plaque Psoriasis

by Swindell, William R., Xing, Xianying, Stuart, Philip E., Chen, Cynthia S., Aphale, Abhishek, Nair, Rajan P., Voorhees, John J., Elder, James T., Johnston, Andrew, Gudjonsson, Johann E.
Published 2012

Association of β-defensin copy number and psoriasis in three cohorts of European origin

by Stuart, Philip E, Hüffmeier, Ulrike, Nair, Rajan P, Palla, Raquel, Tejasvi, Trilokraj, Schalkwijk, Joost, Elder, James T, Reis, Andre, Armour, John AL
Published 2012

A Single SNP Surrogate for Genotyping HLA-C*06:02 in Diverse Populations

by Stuart, Philip E., Tejasvi, Trilokraj, Shaiq, Pakeeza A., Kullavanijaya, Preya, Qamar, Raheel, Raja, Ghazala K., Li, Yanming, Voorhees, John J., Abecasis, Goncalo R., Elder, James T., Nair, Rajan P.
Published 2014

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

by Li, Bingshan, Tsoi, Lam C., Swindell, William R., Gudjonsson, Johann E., Tejasvi, Trilokraj, Johnston, Andrew, Ding, Jun, Stuart, Philip E., Xing, Xianying, Kochkodan, James J., Voorhees, John J., Kang, Hyun M., Nair, Rajan P., Abecasis, Goncalo R., Elder, James T.
Published 2014

Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

by Swindell, William R., Remmer, Henriette A., Sarkar, Mrinal K., Xing, Xianying, Barnes, Drew H., Wolterink, Liza, Voorhees, John J., Nair, Rajan P., Johnston, Andrew, Elder, James T., Gudjonsson, Johann E.
Published 2015

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

by Swindell, William R., Johnston, Andrew, Carbajal, Steve, Han, Gangwen, Wohn, Christian, Lu, Jun, Xing, Xianying, Nair, Rajan P., Voorhees, John J., Elder, James T., Wang, Xiao-Jing, Sano, Shigetoshi, Prens, Errol P., DiGiovanni, John, Pittelkow, Mark R., Ward, Nicole L., Gudjonsson, Johann E.
Published 2011

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin

by Tsoi, Lam C, Iyer, Matthew K, Stuart, Philip E, Swindell, William R, Gudjonsson, Johann E, Tejasvi, Trilokraj, Sarkar, Mrinal K, Li, Bingshan, Ding, Jun, Voorhees, John J, Kang, Hyun M, Nair, Rajan P, Chinnaiyan, Arul M, Abecasis, Goncalo R, Elder, James T
Published 2015

Genome-wide meta-analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL

by Ellinghaus, Eva, Stuart, Philip E., Ellinghaus, David, Nair, Rajan P., Debrus, Sophie, Raelson, John V., Belouchi, Majid, Tejasvi, Trilokraj, Li, Yanming, Tsoi, Lam C., Onken, Anna T., Esko, Tonu, Metspalu, Andres, Rahman, Proton, Gladman, Dafna D., Bowcock, Anne M., Helms, Cynthia, Krueger, Gerald G., Koks, Sulev, Kingo, Külli, Gieger, Christian, Wichmann, H. Erich, Mrowietz, Ulrich, Weidinger, Stephan, Schreiber, Stefan, Abecasis, Gonçalo R., Elder, James T., Weichenthal, Michael, Franke, Andre
Published 2011

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

by Tsoi, Lam C, Spain, Sarah L, Ellinghaus, Eva, Stuart, Philip E, Capon, Francesca, Knight, Jo, Tejasvi, Trilokraj, Kang, Hyun M, Allen, Michael H, Lambert, Sylviane, Stoll, Stefan, Weidinger, Stephan, Gudjonsson, Johann E, Koks, Sulev, Kingo, Külli, Esko, Tonu, Das, Sayantan, Metspalu, Andres, Weichenthal, Michael, Enerback, Charlotta, Krueger, Gerald G., Voorhees, John J, Chandran, Vinod, Rosen, Cheryl F, Rahman, Proton, Gladman, Dafna D, Reis, Andre, Nair, Rajan P, Franke, Andre, Barker, Jonathan NWN, Abecasis, Goncalo R, Trembath, Richard C, Elder, James T
Published 2015

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

by Koch, Manja, Baurecht, Hansjörg, Ried, Janina S., Rodriguez, Elke, Schlesinger, Sabrina, Volks, Natalie, Gieger, Christian, Rückert, Ina-Maria, Heinrich, Luise, Willenborg, Christina, Smith, Catherine, Peters, Annette, Thorand, Barbara, Koenig, Wolfgang, Lamina, Claudia, Jansen, Henning, Kronenberg, Florian, Seissler, Jochen, Thiery, Joachim, Rathmann, Wolfgang, Schunkert, Heribert, Erdmann, Jeanette, Barker, Jonathan, Nair, Rajan P, Tsoi, Lam C, Elder, James T, Mrowietz, Ulrich, Weichenthal, Michael, Mucha, Sören, Schreiber, Stefan, Franke, Andre, Schmitt, Jochen, Lieb, Wolfgang, Weidinger, Stephan
Published 2015

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

by Lenz, Tobias L., Deutsch, Aaron J., Han, Buhm, Hu, Xinli, Okada, Yukinori, Eyre, Stephen, Knapp, Michael, Zhernakova, Alexandra, Huizinga, Tom W.J., Abecasis, Goncalo, Becker, Jessica, Boeckxstaens, Guy E., Chen, Wei-Min, Franke, Andre, Gladman, Dafna D., Gockel, Ines, Gutierrez-Achury, Javier, Martin, Javier, Nair, Rajan P., Nöthen, Markus M., Onengut-Gumuscu, Suna, Rahman, Proton, Rantapää-Dahlqvist, Solbritt, Stuart, Philip E., Tsoi, Lam C., Van Heel, David A., Worthington, Jane, Wouters, Mira M., Klareskog, Lars, Elder, James T., Gregersen, Peter K., Schumacher, Johannes, Rich, Stephen S., Wijmenga, Cisca, Sunyaev, Shamil R., de Bakker, Paul I.W., Raychaudhuri, Soumya
Published 2015

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells

by Li, Jin, Jørgensen, Silje F., Maggadottir, S. Melkorka, Bakay, Marina, Warnatz, Klaus, Glessner, Joseph, Pandey, Rahul, Salzer, Ulrich, Schmidt, Reinhold E., Perez, Elena, Resnick, Elena, Goldacker, Sigune, Buchta, Mary, Witte, Torsten, Padyukov, Leonid, Videm, Vibeke, Folseraas, Trine, Atschekzei, Faranaz, Elder, James T., Nair, Rajan P., Winkelmann, Juliane, Gieger, Christian, Nöthen, Markus M, Büning, Carsten, Brand, Stephan, Sullivan, Kathleen E., Orange, Jordan S., Fevang, Børre, Schreiber, Stefan, Lieb, Wolfgang, Aukrust, Pål, Chapel, Helen, Cunningham-Rundles, Charlotte, Franke, Andre, Karlsen, Tom H., Grimbacher, Bodo, Hakonarson, Hakon, Hammarström, Lennart, Ellinghaus, Eva
Published 2015

Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity

by Tsoi, Lam C, Spain, Sarah L, Knight, Jo, Ellinghaus, Eva, Stuart, Philip E, Capon, Francesca, Ding, Jun, Li, Yanming, Tejasvi, Trilokraj, Gudjonsson, Johann E., Kang, Hyun M, Allen, Michael H, McManus, Ross, Novelli, Giuseppe, Samuelsson, Lena, Schalkwijk, Joost, Ståhle, Mona, Burden, A. David, Smith, Catherine H, Cork, Michael J, Estivill, Xavier, Bowcock, Anne M, Krueger, Gerald G., Weger, Wolfgang, Worthington, Jane, Tazi-Ahnini, Rachid, Nestle, Frank O, Hayday, Adrian, Hoffmann, Per, Winkelmann, Juliane, Wijmenga, Cisca, Langford, Cordelia, Edkins, Sarah, Andrews, Robert, Blackburn, Hannah, Strange, Amy, Band, Gavin, Pearson, Richard D, Vukcevic, Damjan, Spencer, Chris CA, Deloukas, Panos, Mrowietz, Ulrich, Schreiber, Stefan, Weidinger, Stephan, Koks, Sulev, Kingo, Külli, Esko, Tonu, Metspalu, Andres, Lim, Henry W, Voorhees, John J, Weichenthal, Michael, Wichmann, H. Erich, Chandran, Vinod, Rosen, Cheryl F, Rahman, Proton, Gladman, Dafna D, Griffiths, Christopher EM, Reis, Andre, Kere, Juha, Nair, Rajan P, Franke, Andre, Barker, Jonathan NWN, Abecasis, Goncalo R, Elder, James T, Trembath, Richard C
Published 2012

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

by Prins, Bram. P., Abbasi, Ali, Wong, Anson, Vaez, Ahmad, Nolte, Ilja, Franceschini, Nora, Stuart, Philip E., Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P., Valdes, Ana M., Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D., Tsoi, Lam C., Evangelou, Evangelos, Nair, Rajan P., Grant, Struan F. A., Polychronakos, Constantin, Radstake, Timothy R. D., van Heel, David A., Dunstan, Melanie L., Wood, Nicholas W., Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Markus, Hugh S., Elder, James T., Knight, Jo, Arking, Dan E., Spector, Timothy D., Koeleman, Bobby P. C., van Duijn, Cornelia M., Martin, Javier, Morris, Andrew P., Weersma, Rinse K., Wijmenga, Cisca, Munroe, Patricia B., Perry, John R. B., Pouget, Jennie G., Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z.
Published 2016