The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice

by Pani, Giovanni, Siminovitch, Katherine A., Paige, Christopher J.
Published 1997

Fyn and PTP-PEST–mediated Regulation of Wiskott-Aldrich Syndrome Protein (WASp) Tyrosine Phosphorylation Is Required for Coupling T Cell Antigen Receptor Engagement to WASp Effecto...

by Badour, Karen, Zhang, Jinyi, Shi, Fabio, Leng, Yan, Collins, Michael, Siminovitch, Katherine A.
Published 2004

Multiparameter Phospho-Flow Analysis of Lymphocytes in Early Rheumatoid Arthritis: Implications for Diagnosis and Monitoring Drug Therapy

by Galligan, Carole L., Siebert, Janet C., Siminovitch, Katherine A., Keystone, Edward C., Bykerk, Vivian, Perez, Omar D., Fish, Eleanor N.
Published 2009

The Intersectin 2 Adaptor Links Wiskott Aldrich Syndrome Protein (WASp)-mediated Actin Polymerization to T Cell Antigen Receptor Endocytosis

by McGavin, Mary K.H., Badour, Karen, Hardy, Lynne A., Kubiseski, Terrance J., Zhang, Jinyi, Siminovitch, Katherine A.
Published 2001

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance

by Xu, Elaine, Charbonneau, Alexandre, Rolland, Yannève, Bellmann, Kerstin, Pao, Lily, Siminovitch, Katherine A., Neel, Benjamin G., Beauchemin, Nicole, Marette, André
Published 2012

Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis

by Xie, Gang, Lu, Yue, Sun, Ye, Zhang, Steven Shiyang, Keystone, Edward Clark, Gregersen, Peter K, Plenge, Robert M, Amos, Christopher I, Siminovitch, Katherine A
Published 2013

Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization

by Dong, Baoxia, Zhang, Steven S., Gao, Wen, Su, Haichun, Chen, Jun, Jin, Fuzi, Bhargava, Ajay, Chen, Xiequn, Jorgensen, Lars, Alberts, Arthur S., Zhang, Jinyi, Siminovitch, Katherine A.
Published 2013

Incremental predictive value of deep crypts in the basal inferoseptum in the setting of hypertrophic cardiomyopathy

by Deva, Djeven P, Williams, Lynne K, Care, Melanie, Siminovitch, Katherine A, Moshonov, Hadas, Wintersperger, Bernd J, Rakowski, Harry, Crean, Andrew M
Published 2013

Efficient Production of sTNFRII-gAD Fusion Protein in Large Quantity by Use of the Modified CHO-S Cell Expression System

by Cai, Qinzhen, Zhao, Ai, Yuting Yin, Ma, Lisha, Jiao, Zhenzhen, Zhi, Huilin, Lai, Shouhua, Cheng, Sha, Yang, Hongmei, Lu, Yinxiang, Siminovitch, Katherine A., Gao, Jimin
Published 2014

Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes

by Zhang, Jinyi, Shehabeldin, Amro, da Cruz, Luis A.G., Butler, Jeffrey, Somani, Ally-Khan, McGavin, Mary, Kozieradzki, Ivona, dos Santos, Antonio O., Nagy, Andras, Grinstein, Sergio, Penninger, Josef M., Siminovitch, Katherine A.
Published 1999

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

by Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A., Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A., Bae, Sang-Cheol, Plenge, Robert M., Gregersen, Peter K., de Bakker, Paul I.W.
Published 2012

Classical HLA-DRB1 and DPB1 Alleles Account for HLA Associations with Primary Biliary Cirrhosis

by Invernizzi, Pietro, Ransom, Michael, Raychaudhuri, Soumya, Kosoy, Roman, Lleo, Ana, Shigeta, Russell, Franke, Andre, Bossa, Fabrizio, Amos, Christopher I., Gregersen, Peter K., Siminovitch, Katherine A., Cusi, Daniele, de Bakker, Paul I.W., Podda, Mauro, Gershwin, M. Eric, Seldin, Michael F.
Published 2012

Pervasive Sharing of Genetic Effects in Autoimmune Disease

by Cotsapas, Chris, Voight, Benjamin F., Rossin, Elizabeth, Lage, Kasper, Neale, Benjamin M., Wallace, Chris, Abecasis, Gonçalo R., Barrett, Jeffrey C., Behrens, Timothy, Cho, Judy, De Jager, Philip L., Elder, James T., Graham, Robert R., Gregersen, Peter, Klareskog, Lars, Siminovitch, Katherine A., van Heel, David A., Wijmenga, Cisca, Worthington, Jane, Todd, John A., Hafler, David A., Rich, Stephen S., Daly, Mark J.
Published 2011

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

by Mkhikian, Haik, Grigorian, Ani, Li, Carey F., Chen, Hung-Lin, Newton, Barbara, Zhou, Raymond W., Beeton, Christine, Torossian, Sevan, Tatarian, Gevork Grikor, Lee, Sung-Uk, Lau, Ken, Walker, Erin, Siminovitch, Katherine A., Chandy, K. George, Yu, Zhaoxia, Dennis, James W., Demetriou, Michael
Published 2011

Tyrosine phosphatase MEG2 modulates murine development and platelet and lymphocyte activation through secretory vesicle function

by Wang, Yingchun, Vachon, Eric, Zhang, Jinyi, Cherepanov, Vera, Kruger, Joshua, Li, Jun, Saito, Kan, Shannon, Patrick, Bottini, Nunzio, Huynh, Huong, Ni, Heyu, Yang, Hong, McKerlie, Colin, Quaggin, Sue, Zhao, Zhizhuang Joe, Marsden, Philip A., Mustelin, Tomas, Siminovitch, Katherine A., Downey, Gregory P.
Published 2005

Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway

by Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J., Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L., Siminovitch, Katherine A., Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K., Worthington, Jane, Gupta, Namrata, Clemons, Paul A., Stahl, Eli, Tolliday, Nicola, Plenge, Robert M.
Published 2013

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

by Cordell, Heather J., Han, Younghun, Mells, George F., Li, Yafang, Hirschfield, Gideon M., Greene, Casey S., Xie, Gang, Juran, Brian D., Zhu, Dakai, Qian, David C., Floyd, James A. B., Morley, Katherine I., Prati, Daniele, Lleo, Ana, Cusi, Daniele, Gershwin, M. Eric, Anderson, Carl A., Lazaridis, Konstantinos N., Invernizzi, Pietro, Seldin, Michael F., Sandford, Richard N., Amos, Christopher I., Siminovitch, Katherine A.
Published 2015

Systemic juvenile idiopathic arthritis is associated with HLA-DRB1 in Europeans and Americans of European descent

by Ombrello, Michael, Remmers, Elaine F, Grom, Alexei A, Thomson, Wendy, Martini, Alberto, Gattorno, Marco, Ozen, Seza, Gul, Ahmet, Bohnsack, John F, Zeft, Andrew S, Mellins, Elizabeth D, Park, Jane L, Len, Claudio, Satorius, Colleen, Russo, Ricardo AG, Finkel, Terri H, Yeung, Rae SM, Schneider, Rayfel, Prahalad, Sampath, Glass, David N, Allen, Roger C, Wulffraat, Nico, Quartier, Pierre, Hilario, Maria Odete E, Murray, Kevin, Oliveira, Sheila, Anton, Jordi, Hinks, Anne, Zeggini, Eleftheria, Langefeld, Carl, Thompson, Susan, Chaitow, Jeffrey, Ellis, Justine, Singh, Davinder, Cavalvanti, Andre, Bica, Blanca, Sztajnbok, Flavio, Hakonarson, Hakon, Siminovitch, Katherine A, Minden, Kirsten, Haas, Peter, Schwarz, Tobias, Kastner, Daniel L, Woo, Patricia
Published 2012

Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene

by Okada, Yukinori, Diogo, Dorothee, Greenberg, Jeffrey D., Mouassess, Faten, Achkar, Walid A. L., Fulton, Robert S., Denny, Joshua C., Gupta, Namrata, Mirel, Daniel, Gabriel, Stacy, Li, Gang, Kremer, Joel M., Pappas, Dimitrios A., Carroll, Robert J., Eyler, Anne E., Trynka, Gosia, Stahl, Eli A., Cui, Jing, Saxena, Richa, Coenen, Marieke J. H., Guchelaar, Henk-Jan, Huizinga, Tom W. J., Dieudé, Philippe, Mariette, Xavier, Barton, Anne, Canhão, Helena, Fonseca, João E., de Vries, Niek, Tak, Paul P., Moreland, Larry W., Bridges, S. Louis, Miceli-Richard, Corinne, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Raj, Towfique, De Jager, Philip L., Raychaudhuri, Soumya, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Siminovitch, Katherine A., Gregersen, Peter K., Mardis, Elaine R., Arayssi, Thurayya, Kazkaz, Layla A., Plenge, Robert M.
Published 2014

Genetic variants at CD28, PRDM1, and CD2/CD58 are associated with rheumatoid arthritis risk

by Raychaudhuri, Soumya, Thomson, Brian P., Remmers, Elaine F., Eyre, Stephen, Hinks, Anne, Guiducci, Candace, Catanese, Joseph J., Xie, Gang, Stahl, Eli A., Chen, Robert, Alfredsson, Lars, Amos, Christopher I., Ardlie, Kristin G., Barton, Anne, Bowes, John, Burtt, Noel P., Chang, Monica, Coblyn, Jonathan, Costenbader, Karen H., Criswell, Lindsey A., Crusius, J. Bart A., Cui, Jing, De Jager, Phillip L., Ding, Bo, Emery, Paul, Flynn, Edward, Harrison, Pille, Hocking, Lynne J., Huizinga, Tom W. J., Kastner, Daniel L., Ke, Xiayi, Kurreeman, Fina A. S., Lee, Annette T., Liu, Xiangdong, Li, Yonghong, Martin, Paul, Morgan, Ann W., Padyukov, Leonid, Reid, David M., Seielstad, Mark, Seldin, Michael F., Shadick, Nancy A., Steer, Sophia, Tak, Paul P., Thomson, Wendy, van der Helm-van Mil, Annette H. M., van der Horst-Bruinsma, Irene E., Weinblatt, Michael E., Wilson, Anthony G., Wolbink, Gert Jan, Wordsworth, Paul, Altshuler, David, Karlson, Elizabeth W., Toes, Rene E. M., de Vries, Niek, Begovich, Ann B., Siminovitch, Katherine A., Worthington, Jane, Klareskog, Lars, Gregersen, Peter K., Daly, Mark J., Plenge, Robert M.
Published 2009