Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 Cells

by Leister, Kristin P, Huang, Ruili, Goodwin, Bonnie L, Chen, Andrew, Austin, Christopher P, Xia, Menghang
Published 2011

Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data

by Kim, Marlene Thai, Huang, Ruili, Sedykh, Alexander, Wang, Wenyi, Xia, Menghang, Zhu, Hao
Published 2015

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

by Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Xiao, Jingwei, Li, Linhao, Heyward, Scott, Xia, Menghang, Wang, Hongbing
Published 2015

Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor

by Hsu, Chia-Wen, Zhao, Jinghua, Huang, Ruili, Hsieh, Jui-Hua, Hamm, Jon, Chang, Xiaoqing, Houck, Keith, Xia, Menghang
Published 2014

Identification of repurposed small molecule drugs for chordoma therapy

by Xia, Menghang, Huang, Ruili, Sakamuru, Srilatha, Alcorta, David, Cho, Ming-Hsuang, Lee, Dae-Hee, Park, Deric M, Kelley, Michael J, Sommer, Josh, Austin, Christopher P
Published 2013

Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

by Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
Published 2012

Identification of Thyroid Hormone Receptor Active Compounds Using a Quantitative High-Throughput Screening Platform

by Freitas, Jaime, Miller, Nicole, Mengeling, Brenda J., Xia, Menghang, Huang, Ruili, Houck, Keith, Rietjens, Ivonne M.C.M., Furlow, J. David, Murk, Albertinka J.
Published 2014

Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization

by Huang, Ruili, Xia, Menghang, Sakamuru, Srilatha, Zhao, Jinghua, Shahane, Sampada A., Attene-Ramos, Matias, Zhao, Tongan, Austin, Christopher P., Simeonov, Anton
Published 2016

Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wil...

by Vazquez-Ortiz, Guelaguetza, Chisholm, Cristine, Xu, Xiaoling, Lahusen, Tyler J, Li, Cuiling, Sakamuru, Srilatha, Huang, Ruili, Thomas, Craig J, Xia, Menghang, Deng, Chuxia
Published 2014

Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

by Attene-Ramos, Matias S., Huang, Ruili, Michael, Sam, Witt, Kristine L., Richard, Ann, Tice, Raymond R., Simeonov, Anton, Austin, Christopher P., Xia, Menghang
Published 2014

Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling

by Hsu, Chia-Wen, Huang, Ruili, Khuc, Thai, Shou, David, Bullock, Joshua, Grooby, Suzanne, Griffin, Sue, Zou, Chaozhong, Little, Annette, Astley, Holly, Xia, Menghang
Published 2016

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

by Thorne, Natasha, Malik, Nasir, Shah, Sonia, Zhao, Jean, Class, Bradley, Aguisanda, Francis, Southall, Noel, Xia, Menghang, McKew, John C., Rao, Mahendra, Zheng, Wei
Published 2016

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

by Huang, Ruili, Xia, Menghang, Cho, Ming-Hsuang, Sakamuru, Srilatha, Shinn, Paul, Houck, Keith A., Dix, David J., Judson, Richard S., Witt, Kristine L., Kavlock, Robert J., Tice, Raymond R., Austin, Christopher P.
Published 2011

Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals

by Rotroff, Daniel M., Dix, David J., Houck, Keith A., Knudsen, Thomas B., Martin, Matthew T., McLaurin, Keith W., Reif, David M., Crofton, Kevin M., Singh, Amar V., Xia, Menghang, Huang, Ruili, Judson, Richard S.
Published 2012

5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary

by Khare, Tarang, Pai, Shraddha, Koncevicius, Karolis, Pal, Mrinal, Kriukiene, Edita, Liutkeviciute, Zita, Irimia, Manuel, Jia, Peixin, Ptak, Carolyn, Xia, Menghang, Tice, Raymond, Tochigi, Mamoru, Moréra, Solange, Nazarians, Anaies, Belsham, Denise, Wong, Albert H. C., Blencowe, Benjamin J., Wang, Sun Chong, Kapranov, Philipp, Kustra, Rafal, Labrie, Viviane, Klimasauskas, Saulius, Petronis, Arturas
Published 2012

A Novel Chordoma Xenograft Allows In Vivo Drug Testing and Reveals the Importance of NF-κB Signaling in Chordoma Biology

by Trucco, Matteo M., Awad, Ola, Wilky, Breelyn A., Goldstein, Seth D., Huang, Ruili, Walker, Robert L., Shah, Preeti, Katuri, Varalakshmi, Gul, Naheed, Zhu, Yuelin J., McCarthy, Edward F., Paz-Priel, Ido, Meltzer, Paul S., Austin, Christopher P., Xia, Menghang, Loeb, David M.
Published 2013

Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Mode...

by Martinez, Natalia J., Rai, Ganesha, Yasgar, Adam, Lea, Wendy A., Sun, Hongmao, Wang, Yuhong, Luci, Diane K., Yang, Shyh-Ming, Nishihara, Kana, Takeda, Shunichi, Mohiuddin, Earnshaw, Irina, Okada, Tetsuya, Mori, Kazutoshi, Wilson, Kelli, Riggins, Gregory J., Xia, Menghang, Grimaldi, Maurizio, Jadhav, Ajit, Maloney, David J., Simeonov, Anton
Published 2016

A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models

by Martinez, Natalia J., Rai, Ganesha, Yasgar, Adam, Lea, Wendy A., Sun, Hongmao, Wang, Yuhong, Luci, Diane K., Yang, Shyh-Ming, Nishihara, Kana, Takeda, Shunichi, Sagor, Mohiuddin, Earnshaw, Irina, Okada, Tetsuya, Mori, Kazutoshi, Wilson, Kelli, Riggins, Gregory J., Xia, Menghang, Grimaldi, Maurizio, Jadhav, Ajit, Maloney, David J., Simeonov, Anton
Published 2016

Prediction of human population responses to toxic compounds by a collaborative competition

by Eduati, Federica, Mangravite, Lara M., Wang, Tao, Tang, Hao, Bare, J. Christopher, Huang, Ruili, Norman, Thea, Kellen, Mike, Menden, Michael P., Yang, Jichen, Zhan, Xiaowei, Zhong, Rui, Xiao, Guanghua, Xia, Menghang, Abdo, Nour, Kosyk, Oksana, Friend, Stephen, Dearry, Allen, Simeonov, Anton, Tice, Raymond, Rusyn, Ivan, Wright, Fred A., Stolovitzky, Gustavo, Xie, Yang, Saez-Rodriguez, Julio
Published 2015

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

by Abdo, Nour, Xia, Menghang, Brown, Chad C., Kosyk, Oksana, Huang, Ruili, Sakamuru, Srilatha, Zhou, Yi-Hui, Jack, John R., Gallins, Paul, Xia, Kai, Li, Yun, Chiu, Weihsueh A., Motsinger-Reif, Alison A., Austin, Christopher P., Tice, Raymond R., Rusyn, Ivan, Wright, Fred A.
Published 2015