Identification of repurposed small molecule drugs for chordoma therapy

by Xia, Menghang, Huang, Ruili, Sakamuru, Srilatha, Alcorta, David, Cho, Ming-Hsuang, Lee, Dae-Hee, Park, Deric M, Kelley, Michael J, Sommer, Josh, Austin, Christopher P
Published 2013

Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization

by Huang, Ruili, Xia, Menghang, Sakamuru, Srilatha, Zhao, Jinghua, Shahane, Sampada A., Attene-Ramos, Matias, Zhao, Tongan, Austin, Christopher P., Simeonov, Anton
Published 2016

Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wil...

by Vazquez-Ortiz, Guelaguetza, Chisholm, Cristine, Xu, Xiaoling, Lahusen, Tyler J, Li, Cuiling, Sakamuru, Srilatha, Huang, Ruili, Thomas, Craig J, Xia, Menghang, Deng, Chuxia
Published 2014

Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors

by Huang, Ruili, Xia, Menghang, Cho, Ming-Hsuang, Sakamuru, Srilatha, Shinn, Paul, Houck, Keith A., Dix, David J., Judson, Richard S., Witt, Kristine L., Kavlock, Robert J., Tice, Raymond R., Austin, Christopher P.
Published 2011

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

by Abdo, Nour, Xia, Menghang, Brown, Chad C., Kosyk, Oksana, Huang, Ruili, Sakamuru, Srilatha, Zhou, Yi-Hui, Jack, John R., Gallins, Paul, Xia, Kai, Li, Yun, Chiu, Weihsueh A., Motsinger-Reif, Alison A., Austin, Christopher P., Tice, Raymond R., Rusyn, Ivan, Wright, Fred A.
Published 2015

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway

by Huang, Ruili, Sakamuru, Srilatha, Martin, Matt T., Reif, David M., Judson, Richard S., Houck, Keith A., Casey, Warren, Hsieh, Jui-Hua, Shockley, Keith R., Ceger, Patricia, Fostel, Jennifer, Witt, Kristine L., Tong, Weida, Rotroff, Daniel M., Zhao, Tongan, Shinn, Paul, Simeonov, Anton, Dix, David J., Austin, Christopher P., Kavlock, Robert J., Tice, Raymond R., Xia, Menghang
Published 2014