Mitochondrial disorders in children: toward development of small‐molecule treatment strategies

by Koopman, Werner JH, Beyrath, Julien, Fung, Cheuk‐Wing, Koene, Saskia, Rodenburg, Richard J, Willems, Peter HGM, Smeitink, Jan AM
Published 2016

Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells

by Forkink, Marleen, Basit, Farhan, Teixeira, José, Swarts, Herman G., Koopman, Werner J.H., Willems, Peter H.G.M.
Published 2015

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth

by Schöckel, Laura, Glasauer, Andrea, Basit, Farhan, Bitschar, Katharina, Truong, Hoa, Erdmann, Gerrit, Algire, Carolyn, Hägebarth, Andrea, Willems, Peter HGM, Kopitz, Charlotte, Koopman, Werner JH, Héroult, Mélanie
Published 2015

Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates

by Sieprath, Tom, Corne, Tobias DJ, Nooteboom, Marco, Grootaert, Charlotte, Rajkovic, Andreja, Buysschaert, Benjamin, Robijns, Joke, Broers, Jos LV, Ramaekers, Frans CS, Koopman, Werner JH, Willems, Peter HGM, De Vos, Winnok H
Published 2015