SREBF1 links lipogenesis to mitophagy and sporadic Parkinson disease

by Ivatt, Rachael M, Whitworth, Alexander J
Published 2014

The many faces of mitophagy

by Ivatt, Rachael M, Whitworth, Alexander J
Published 2014

VPS35 pathogenic mutations confer no dominant toxicity but partial loss of function in Drosophila and genetically interact with parkin

by Malik, Bilal R., Godena, Vinay K., Whitworth, Alexander J.
Published 2015

Axonal transport defects are a common phenotype in Drosophila models of ALS

by Baldwin, Katie R., Godena, Vinay K., Hewitt, Victoria L., Whitworth, Alexander J.
Published 2016

Modeling Pathogenic Mutations of Human Twinkle in Drosophila Suggests an Apoptosis Role in Response to Mitochondrial Defects

by Sanchez-Martinez, Alvaro, Calleja, Manuel, Peralta, Susana, Matsushima, Yuichi, Hernandez-Sierra, Rosana, Whitworth, Alexander J., Kaguni, Laurie S., Garesse, Rafael
Published 2012

Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

by Sanchez-Martinez, Alvaro, Beavan, Michelle, Gegg, Matthew E., Chau, Kai-Yin, Whitworth, Alexander J., Schapira, Anthony H. V.
Published 2016

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

by Pogson, Joe H., Ivatt, Rachael M., Sanchez-Martinez, Alvaro, Tufi, Roberta, Wilson, Emma, Mortiboys, Heather, Whitworth, Alexander J.
Published 2014

Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1

by Kieper, Nicole, Holmström, Kira M., Ciceri, Dalila, Fiesel, Fabienne C., Wolburg, Hartwig, Ziviani, Elena, Whitworth, Alexander J., Martins, L. Miguel, Kahle, Philipp J., Krüger, Rejko
Published 2010

Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE*

by Filograna, Roberta, Godena, Vinay K., Sanchez-Martinez, Alvaro, Ferrari, Emanuele, Casella, Luigi, Beltramini, Mariano, Bubacco, Luigi, Whitworth, Alexander J., Bisaglia, Marco
Published 2016

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

by Godena, Vinay K., Brookes-Hocking, Nicholas, Moller, Annekathrin, Shaw, Gary, Oswald, Matthew, Sancho, Rosa M., Miller, Christopher C. J., Whitworth, Alexander J., De Vos, Kurt J.
Published 2014

Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations

by Woodroof, Helen I., Pogson, Joe H., Begley, Mike, Cantley, Lewis C., Deak, Maria, Campbell, David G., van Aalten, Daan M. F., Whitworth, Alexander J., Alessi, Dario R., Muqit, Miratul M. K.
Published 2011

The Parkinson’s disease genes Fbxo7 and Parkin interact to mediate mitophagy

by Burchell, Victoria S, Nelson, David E, Sanchez-Martinez, Alvaro, Delgado-Camprubi, Marta, Ivatt, Rachael M, Pogson, Joe H, Randle, Suzanne J, Wray, Selina, Lewis, Patrick A, Houlden, Henry, Abramov, Andrey Y, Hardy, John, Wood, Nicholas W, Whitworth, Alexander J, Laman, Heike, Plun-Favreau, Helene
Published 2013

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

by Webster, Christopher P, Smith, Emma F, Bauer, Claudia S, Moller, Annekathrin, Hautbergue, Guillaume M, Ferraiuolo, Laura, Myszczynska, Monika A, Higginbottom, Adrian, Walsh, Matthew J, Whitworth, Alexander J, Kaspar, Brian K, Meyer, Kathrin, Shaw, Pamela J, Grierson, Andrew J, De Vos, Kurt J
Published 2016