Targeted sequencing of lung function loci in chronic obstructive pulmonary disease cases and controls

by Artigas, María Soler, Wain, Louise V., Shrine, Nick, McKeever, Tricia M., Sayers, Ian, Hall, Ian P., Tobin, Martin D.
Published 2017

The vitamin D binding protein axis modifies disease severity in Lymphangioleiomyomatosis

by Miller, Suzanne, Coveney, Claire, Johnson, Janice, Farmaki, Aliki-Eleni, Gupta, Nishant, Tobin, Martin D., Wain, Louise V., McCormack, Francis, Boocock, David J., Johnson, Simon R.
Published 2018

Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

by Kerr, Shona M, Campbell, Archie, Murphy, Lee, Hayward, Caroline, Jackson, Cathy, Wain, Louise V, Tobin, Martin D, Dominiczak, Anna, Morris, Andrew, Smith, Blair H, Porteous, David J
Published 2013

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome)

by Glover, Mark, Ware, James S., Henry, Amanda, Wolley, Martin, Walsh, Roddy, Wain, Louise V., Xu, Shengxin, Van’t Hoff, William G., Tobin, Martin D., Hall, Ian P., Cook, Stuart, Gordon, Richard D., Stowasser, Michael, O’Shaughnessy, Kevin M.
Published 2014

Copy Number Variation of the Beta-Defensin Genes in Europeans: No Supporting Evidence for Association with Lung Function, Chronic Obstructive Pulmonary Disease or Asthma

by Wain, Louise V., Odenthal-Hesse, Linda, Abujaber, Razan, Sayers, Ian, Beardsmore, Caroline, Gaillard, Erol A., Chappell, Sally, Dogaru, Cristian M., McKeever, Tricia, Guetta-Baranes, Tamar, Kalsheker, Noor, Kuehni, Claudia E., Hall, Ian P., Tobin, Martin D., Hollox, Edward J.
Published 2014

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction

by Wain, Louise V., Sayers, Ian, Artigas, María Soler, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma’en, Sin, Don D., Bossé, Yohan, Nickle, David C., Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelingsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia M., Shrine, Nick, Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Published 2014

Copy number variation of the beta-defensin genes in Europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma

by Ahuja, Sunil K., Wain, Louise V., Odenthal-Hesse, Linda, Abujaber, Razan, Sayers, Ian, Beardsmore, Caroline, Gaillard, Erol A., Chappell, Sally, Dogaru, Cristian M., McKeever, Tricia M., Guetta-Baranes, Tamar, Kalsheker, Noor, Kuehni, Claudia E., Hall, Ian P., Tobin, Martin D., Hollox, Edward J.
Published 2014

GSTCD and INTS12 regulation and expression in the human lung

by Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Soler Artigas, María, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian, Hall, Ian P.
Published 2013

Age at menarche and lung function: a Mendelian randomization study

by Gill, Dipender, Sheehan, Nuala A., Wielscher, Matthias, Shrine, Nick, Amaral, Andre F. S., Thompson, John R., Granell, Raquel, Leynaert, Bénédicte, Real, Francisco Gómez, Hall, Ian P., Tobin, Martin D., Auvinen, Juha, Ring, Susan M., Jarvelin, Marjo-Riitta, Wain, Louise V., Henderson, John, Jarvis, Deborah, Minelli, Cosetta
Published 2017

Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline

by John, Catherine, Soler Artigas, María, Hui, Jennie, Nielsen, Sune Fallgaard, Rafaels, Nicholas, Paré, Peter D, Hansel, Nadia N., Shrine, Nick, Kilty, Iain, Malarstig, Anders, Jelinsky, Scott A, Vedel-Krogh, Signe, Barnes, Kathleen, Hall, Ian P., Beilby, John, Musk, Arthur W., Nordestgaard, Børge G., James, Alan, Wain, Louise V., Tobin, Martin D.
Published 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

by Wain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., Johnson, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Sayers, Ian, Hall, Ian P.
Published 2017

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

by Ware, James S., Wain, Louise V., Channavajjhala, Sarath K., Jackson, Victoria E., Edwards, Elizabeth, Lu, Run, Siew, Keith, Jia, Wenjing, Shrine, Nick, Kinnear, Sue, Jalland, Mahli, Henry, Amanda P., Clayton, Jenny, O’Shaughnessy, Kevin M., Tobin, Martin D., Schuster, Victor, Cook, Stuart, Hall, Ian P., Glover, Mark
Published 2017

GSTCD and INTS12 Regulation and Expression in the Human Lung

by Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Artigas, María Soler, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian, Hall, Ian P.
Published 2013

Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction

by Wain, Louise V., Sayers, Ian, Soler Artigas, María, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma'en, Sin, Don D., Bossé, Yohan, Nickle, David, Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelinsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia, Shrine, Nick R. G., Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Published 2014

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

by Shrine, Nick, Tobin, Martin D., Schurmann, Claudia, Soler Artigas, María, Hui, Jennie, Lehtimäki, Terho, Raitakari, Olli T., Pennell, Craig E., Ang, Qi Wei, Strachan, David P., Homuth, Georg, Gläser, Sven, Felix, Stephan B., Evans, David M., Henderson, John, Granell, Raquel, Palmer, Lyle J., Huffman, Jennifer, Hayward, Caroline, Scotland, Generation, Malarstig, Anders, Musk, Bill, James, Alan L., Wain, Louise V.
Published 2016

A genome-wide association study in Hispanics/Latinos identifies novel signals for lung function: the Hispanic Community Health Study/Study of Latinos

by Burkart, Kristin M., Sofer, Tamar, London, Stephanie J., Manichaikul, Ani, Hartwig, Fernando P., Yan, Qi, Artigas, María Soler, Avila, Lydiana, Chen, Wei, Thomas, Sonia Davis, Diaz, Alejandro A., Hall, Ian P., Horta, Bernardo L., Kaplan, Robert C., Laurie, Cathy C., Menezes, Ana M., Morrison, Jean V., Oelsner, Elizabeth C., Rastogi, Deepa, Rich, Stephen S., Soto-Quiros, Manuel, Stilp, Adrienne M., Tobin, Martin D., Wain, Louise V., Celedon, Juan C., Barr, R. Graham
Published 2018

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

by Jackson, Victoria E., Ntalla, Ioanna, Sayers, Ian, Morris, Richard, Whincup, Peter, Casas, Juan-Pablo, Amuzu, Antoinette, Choi, Minkyoung, Dale, Caroline, Kumari, Meena, Engmann, Jorgen, Kalsheker, Noor, Chappell, Sally, Guetta-Baranes, Tamar, McKeever, Tricia M., Palmer, Colin N.A., Tavendale, Roger, Holloway, John W., Sayer, Avan A., Dennison, Elaine M., Cooper, Cyrus, Bafadhel, Mona, Barker, Bethan, Brightling, Chris, Bolton, Charlotte E., John, Michelle E., Parker, Stuart G., Moffat, Miriam F., Wardlaw, Andrew J., Connolly, Martin J., Porteous, David J., Smith, Blair H., Padmanabhan, Sandosh, Hocking, Lynne, Stirrups, Kathleen E., Deloukas, Panos, Strachan, David P., Hall, Ian P., Tobin, Martin D., Wain, Louise V.
Published 2016

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

by Wain, Louise V., Shrine, Nick, Miller, Suzanne, Jackson, Victoria E., Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K., Kheirallah, Abdul Kader, Allen, Richard, Cook, James P., Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S., Paré, Peter D., Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L., Thomson, Neil C., Zeggini, Eleftheria, Morris, Andrew P., Marchini, Jonathan, Strachan, David P., Tobin, Martin D., Hall, Ian P.
Published 2015

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

by Jackson, Victoria E, Ntalla, Ioanna, Sayers, Ian, Morris, Richard, Whincup, Peter, Casas, Juan-Pablo, Amuzu, Antoinette, Choi, Minkyoung, Dale, Caroline, Kumari, Meena, Engmann, Jorgen, Kalsheker, Noor, Chappell, Sally, Guetta-Baranes, Tamar, McKeever, Tricia M, Palmer, Colin N A, Tavendale, Roger, Holloway, John W, Sayer, Avan A, Dennison, Elaine M, Cooper, Cyrus, Bafadhel, Mona, Barker, Bethan, Brightling, Chris, Bolton, Charlotte E, John, Michelle E, Parker, Stuart G, Moffat, Miriam F, Wardlaw, Andrew J, Connolly, Martin J, Porteous, David J, Smith, Blair H, Padmanabhan, Sandosh, Hocking, Lynne, Stirrups, Kathleen E, Deloukas, Panos, Strachan, David P, Hall, Ian P, Tobin, Martin D, Wain, Louise V
Published 2016

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

by Wain, Louise V, Shrine, Nick, Miller, Suzanne, Jackson, Victoria E, Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K, Kheirallah, Abdul Kader, Allen, Richard, Cook, James P, Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S, Paré, Peter D, Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L, Thomson, Neil C, Zeggini, Eleftheria, Morris, Andrew P, Marchini, Jonathan, Strachan, David P, Tobin, Martin D, Hall, Ian P
Published 2015