Total particulate matter concentration skews cigarette smoke's gene expression profile

by Dvorkin-Gheva, Anna, Vanderstocken, Gilles, Yildirim, Ali Önder, Brandsma, Corry-Anke, Obeidat, Ma'en, Bossé, Yohan, Hassell, John A., Stampfli, Martin R.
Published 2016

Impact of Statins on Gene Expression in Human Lung Tissues

by Lane, Jérôme, van Eeden, Stephan F., Obeidat, Ma’en, Sin, Don D., Tebbutt, Scott J., Timens, Wim, Postma, Dirkje S., Laviolette, Michel, Paré, Peter D., Bossé, Yohan
Published 2015

The Effect of Statins on Blood Gene Expression in COPD

by Obeidat, Ma’en, Fishbane, Nick, Nie, Yunlong, Chen, Virginia, Hollander, Zsuzsanna, Tebbutt, Scott J., Bossé, Yohan, Ng, Raymond T., Miller, Bruce E., McManus, Bruce, Rennard, Stephen, Paré, Peter D., Sin, Don D.
Published 2015

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction

by Wain, Louise V., Sayers, Ian, Artigas, María Soler, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma’en, Sin, Don D., Bossé, Yohan, Nickle, David C., Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelingsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia M., Shrine, Nick, Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Published 2014

GSTCD and INTS12 regulation and expression in the human lung

by Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Soler Artigas, María, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian, Hall, Ian P.
Published 2013

The Ser82 RAGE variant affects lung function and serum RAGE in smokers and sRAGE production in vitro

by Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P., Sayers, Ian
Published 2016

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

by Wain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., Johnson, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Sayers, Ian, Hall, Ian P.
Published 2017

GSTCD and INTS12 Regulation and Expression in the Human Lung

by Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Artigas, María Soler, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian, Hall, Ian P.
Published 2013

Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction

by Wain, Louise V., Sayers, Ian, Soler Artigas, María, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma'en, Sin, Don D., Bossé, Yohan, Nickle, David, Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelinsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia, Shrine, Nick R. G., Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P., Tobin, Martin D.
Published 2014

The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro

by Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P., Sayers, Ian
Published 2016

Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9)

by Chen, Yu, Zhou, Jie, Cheng, Zhongshan, Yang, Shigui, Chu, Hin, Fan, Yanhui, Li, Cun, Wong, Bosco Ho-Yin, Zheng, Shufa, Zhu, Yixin, Yu, Fei, Wang, Yiyin, Liu, Xiaoli, Gao, Hainv, Yu, Liang, Tang, Linglin, Cui, Dawei, Hao, Ke, Bossé, Yohan, Obeidat, Ma′en, Brandsma, Corry-Anke, Song, You-Qiang, To, Kelvin Kai-Wang, Sham, Pak Chung, Yuen, Kwok-Yung, Li, Lanjuan
Published 2015

Genes related to emphysema are enriched for ubiquitination pathways

by Stepaniants, Sergey, Wang, I-Ming, Boie, Yves, Mortimer, James, Kennedy, Brian, Elliott, Mark, Hayashi, Shizu, Luo, Honglin, Wong, Jerry, Loy, Leanna, Coulter, Silvija, Roberts, Christopher J, Hogg, James C, Sin, Don D, O’Neill, Gary, Crackower, Michael, Morris, Melody, Paré, Peter D, Obeidat, Ma’en
Published 2014

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

by Wain, Louise V., Shrine, Nick, Miller, Suzanne, Jackson, Victoria E., Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K., Kheirallah, Abdul Kader, Allen, Richard, Cook, James P., Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S., Paré, Peter D., Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L., Thomson, Neil C., Zeggini, Eleftheria, Morris, Andrew P., Marchini, Jonathan, Strachan, David P., Tobin, Martin D., Hall, Ian P.
Published 2015

Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels

by Thun, Gian Andri, Imboden, Medea, Ferrarotti, Ilaria, Kumar, Ashish, Obeidat, Ma'en, Zorzetto, Michele, Haun, Margot, Curjuric, Ivan, Couto Alves, Alexessander, Jackson, Victoria E., Albrecht, Eva, Ried, Janina S., Teumer, Alexander, Lopez, Lorna M., Huffman, Jennifer E., Enroth, Stefan, Bossé, Yohan, Hao, Ke, Timens, Wim, Gyllensten, Ulf, Polasek, Ozren, Wilson, James F., Rudan, Igor, Hayward, Caroline, Sandford, Andrew J., Deary, Ian J., Koch, Beate, Reischl, Eva, Schulz, Holger, Hui, Jennie, James, Alan L., Rochat, Thierry, Russi, Erich W., Jarvelin, Marjo-Riitta, Strachan, David P., Hall, Ian P., Tobin, Martin D., Dahl, Morten, Fallgaard Nielsen, Sune, Nordestgaard, Børge G., Kronenberg, Florian, Luisetti, Maurizio, Probst-Hensch, Nicole M.
Published 2013

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

by Wain, Louise V, Shrine, Nick, Miller, Suzanne, Jackson, Victoria E, Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K, Kheirallah, Abdul Kader, Allen, Richard, Cook, James P, Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S, Paré, Peter D, Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L, Thomson, Neil C, Zeggini, Eleftheria, Morris, Andrew P, Marchini, Jonathan, Strachan, David P, Tobin, Martin D, Hall, Ian P
Published 2015

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

by Allen, Richard J., Porte, Joanne, Braybrooke, Rebecca, Flores, Carlos, Fingerlin, Tasha E., Oldham, Justin M., Guillen-Guio, Beatriz, Ma, Shwu-Fan, Okamoto, Tsukasa, John, Alison E., Obeidat, Ma'en, Yang, Ivana V., Henry, Amanda, Hubbard, Richard B., Navaratnam, Vidya, Saini, Gauri, Thompson, Norma, Booth, Helen L., Hart, Simon P., Hill, Mike R., Hirani, Nik, Maher, Toby M., McAnulty, Robin J., Millar, Ann B., Molyneaux, Philip L., Parfrey, Helen, Rassl, Doris M., Whyte, Moira K.B., Fahy, William A., Marshall, Richard P., Oballa, Eunice, Bossé, Yohan, Nickle, David C., Sin, Don D., Timens, Wim, Shrine, Nick, Sayers, Ian, Hall, Ian P., Noth, Imre, Schwartz, David A., Tobin, Martin D., Wain, Louise V., Jenkins, R. Gisli
Published 2017

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

by Obeidat, Ma'en, Hao, Ke, Bossé, Yohan, Nickle, David C., Nie, Yunlong, Postma, Dirkje S., Laviolette, Michel, Sandford, Andrew J., Daley, Denise D., Hogg, James C., Elliott, W. Mark, Fishbane, Nick, Timens, Wim, Hysi, Pirro G., Kaprio, Jaakko, Wilson, James F., Hui, Jennie, Rawal, Rajesh, Schulz, Holger, Stubbe, Beate, Hayward, Caroline, Polasek, Ozren, Järvelin, Marjo-Riitta, Zhao, Jing Hua, Jarvis, Deborah, Kähönen, Mika, Franceschini, Nora, North, Kari E., Loth, Daan W., Brusselle, Guy G., Smith, Albert Vernon, Gudnason, Vilmundur, Bartz, Traci M, Wilk, Jemma B., O'Connor, George T., Cassano, Patricia A., Tang, Wenbo, Wain, Louise V., Artigas, María Soler, Gharib, Sina A., Strachan, David P., Sin, Don D., Tobin, Martin D., London, Stephanie J., Hall, Ian P., Paré, Peter D.
Published 2015

Integrative pathway genomics of lung function and airflow obstruction

by Gharib, Sina A., Loth, Daan W., Soler Artigas, María, Birkland, Timothy P., Wilk, Jemma B., Wain, Louise V., Brody, Jennifer A., Obeidat, Ma'en, Hancock, Dana B., Tang, Wenbo, Rawal, Rajesh, Boezen, H. Marike, Imboden, Medea, Huffman, Jennifer E., Lahousse, Lies, Alves, Alexessander C., Manichaikul, Ani, Hui, Jennie, Morrison, Alanna C., Ramasamy, Adaikalavan, Smith, Albert Vernon, Gudnason, Vilmundur, Surakka, Ida, Vitart, Veronique, Evans, David M., Strachan, David P., Deary, Ian J., Hofman, Albert, Gläser, Sven, Wilson, James F., North, Kari E., Zhao, Jing Hua, Heckbert, Susan R., Jarvis, Deborah L., Probst-Hensch, Nicole, Schulz, Holger, Barr, R. Graham, Jarvelin, Marjo-Riitta, O'Connor, George T., Kähönen, Mika, Cassano, Patricia A., Hysi, Pirro G., Dupuis, Josée, Hayward, Caroline, Psaty, Bruce M., Hall, Ian P., Parks, William C., Tobin, Martin D., London, Stephanie J.
Published 2015

A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample

by Obeidat, Ma'en, Wain, Louise V., Shrine, Nick, Kalsheker, Noor, Artigas, Maria Soler, Repapi, Emmanouela, Burton, Paul R., Johnson, Toby, Ramasamy, Adaikalavan, Zhao, Jing Hua, Zhai, Guangju, Huffman, Jennifer E., Vitart, Veronique, Albrecht, Eva, Igl, Wilmar, Hartikainen, Anna-Liisa, Pouta, Anneli, Cadby, Gemma, Hui, Jennie, Palmer, Lyle J., Hadley, David, McArdle, Wendy L., Rudnicka, Alicja R., Barroso, Inês, Loos, Ruth J. F., Wareham, Nicholas J., Mangino, Massimo, Soranzo, Nicole, Spector, Tim D., Gläser, Sven, Homuth, Georg, Völzke, Henry, Deloukas, Panos, Granell, Raquel, Henderson, John, Grkovic, Ivica, Jankovic, Stipan, Zgaga, Lina, Polašek, Ozren, Rudan, Igor, Wright, Alan F., Campbell, Harry, Wild, Sarah H., Wilson, James F., Heinrich, Joachim, Imboden, Medea, Probst-Hensch, Nicole M., Gyllensten, Ulf, Johansson, Åsa, Zaboli, Ghazal, Mustelin, Linda, Rantanen, Taina, Surakka, Ida, Kaprio, Jaakko, Jarvelin, Marjo-Riitta, Hayward, Caroline, Evans, David M., Koch, Beate, Musk, Arthur William, Elliott, Paul, Strachan, David P., Tobin, Martin D., Sayers, Ian, Hall, Ian P., Consortium, SpiroMeta
Published 2011

Correction: Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study

by Dijkstra, Akkelies E., Smolonska, Joanna, van den Berge, Maarten, Wijmenga, Ciska, Zanen, Pieter, Luinge, Marjan A., Platteel, Mathieu, Lammers, Jan-Willem, Dahlback, Magnus, Tosh, Kerrie, Hiemstra, Pieter S., Sterk, Peter J., Spira, Avi, Vestbo, Jorgen, Nordestgaard, Borge G., Benn, Marianne, Nielsen, Sune F., Dahl, Morten, Verschuren, W. Monique, Picavet, H. Susan J., Smit, Henriette A., Owsijewitsch, Michael, Kauczor, Hans U., de Koning, Harry J., Nizankowska-Mogilnicka, Eva, Mejza, Filip, Nastalek, Pawel, van Diemen, Cleo C., Cho, Michael H., Silverman, Edwin K., Crapo, James D., Beaty, Terri H., Lomas, David A., Bakke, Per, Gulsvik, Amund, Bossé, Yohan, Obeidat, Ma’en, Loth, Daan W., Lahousse, Lies, Rivadeneira, Fernando, Uitterlinden, Andre G., Hofman, Andre, Stricker, Bruno H., Brusselle, Guy G., van Duijn, Cornelia M., Brouwer, Uilke, Koppelman, Gerard H., Vonk, Judith M., Nawijn, Martijn C., Groen, Harry J. M., Timens, Wim, Boezen, H. Marike, Postma, Dirkje S.
Published 2015