Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo

by Németh, Tamás, Futosi, Krisztina, Sitaru, Cassian, Ruland, Jürgen, Mócsai, Attila
Published 2016

The Bcl10–Malt1 complex segregates FcɛRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation

by Klemm, Stefanie, Gutermuth, Jan, Hültner, Lothar, Sparwasser, Tim, Behrendt, Heidrun, Peschel, Christian, Mak, Tak W., Jakob, Thilo, Ruland, Jürgen
Published 2006

Cks1 Is Required for Tumor Cell Proliferation but Not Sufficient to Induce Hematopoietic Malignancies

by Kratzat, Susanne, Nikolova, Viktoriya, Miething, Cornelius, Hoellein, Alexander, Schoeffmann, Stephanie, Gorka, Oliver, Pietschmann, Elke, Illert, Anna-Lena, Ruland, Jürgen, Peschel, Christian, Nilsson, Jonas, Duyster, Justus, Keller, Ulrich
Published 2012

Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

by da Glória Sousa, Maria, Reid, Delyth M., Schweighoffer, Edina, Tybulewicz, Victor, Ruland, Jürgen, Langhorne, Jean, Yamasaki, Sho, Taylor, Philip R., Almeida, Sandro R., Brown, Gordon D.
Published 2011

TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function

by Śledzińska, Anna, Hemmers, Saskia, Mair, Florian, Gorka, Oliver, Ruland, Jürgen, Fairbairn, Lynsey, Nissler, Anja, Müller, Werner, Waisman, Ari, Becher, Burkhard, Buch, Thorsten
Published 2013

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

by Strasser, Dominikus, Neumann, Konstantin, Bergmann, Hanna, Marakalala, Mohlopheni J., Guler, Reto, Rojowska, Anna, Hopfner, Karl-Peter, Brombacher, Frank, Urlaub, Henning, Baier, Gottfried, Brown, Gordon D., Leitges, Michael, Ruland, Jürgen
Published 2012

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

by Roth, Susanne, Bergmann, Hanna, Jaeger, Martin, Yeroslaviz, Assa, Neumann, Konstantin, Koenig, Paul-Albert, Prazeres da Costa, Clarissa, Vanes, Lesley, Kumar, Vinod, Johnson, Melissa, Menacho-Márquez, Mauricio, Habermann, Bianca, Tybulewicz, Victor L., Netea, Mihai, Bustelo, Xosé R., Ruland, Jürgen
Published 2016

Alternative splicing of MALT1 controls signalling and activation of CD4+ T cells

by Meininger, Isabel, Griesbach, Richard A., Hu, Desheng, Gehring, Torben, Seeholzer, Thomas, Bertossi, Arianna, Kranich, Jan, Oeckinghaus, Andrea, Eitelhuber, Andrea C., Greczmiel, Ute, Gewies, Andreas, Schmidt-Supprian, Marc, Ruland, Jürgen, Brocker, Thomas, Heissmeyer, Vigo, Heyd, Florian, Krappmann, Daniel
Published 2016

Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo

by Lutzny, Gloria, Kocher, Thomas, Schmidt-Supprian, Marc, Rudelius, Martina, Klein-Hitpass, Ludger, Finch, Andrew J., Dürig, Jan, Wagner, Michaela, Haferlach, Claudia, Kohlmann, Alexander, Schnittger, Susanne, Seifert, Marc, Wanninger, Stefan, Zaborsky, Nadja, Oostendorp, Robert, Ruland, Jürgen, Leitges, Michael, Kuhnt, Toni, Schäfer, Yvonne, Lampl, Benedikt, Peschel, Christian, Egle, Alexander, Ringshausen, Ingo
Published 2013

The Nlrp3 inflammasome regulates acute graft-versus-host disease

by Jankovic, Dragana, Ganesan, Jayanthi, Bscheider, Michael, Stickel, Natalie, Weber, Felix C., Guarda, Greta, Follo, Marie, Pfeifer, Dietmar, Tardivel, Aubry, Ludigs, Kristina, Bouazzaoui, Abdellatif, Kerl, Katrin, Fischer, Julius C., Haas, Tobias, Schmitt-Gräff, Annette, Manoharan, Anand, Müller, Leonard, Finke, Jürgen, Martin, Stefan F., Gorka, Oliver, Peschel, Christian, Ruland, Jürgen, Idzko, Marco, Duyster, Justus, Holler, Ernst, French, Lars E., Poeck, Hendrik, Contassot, Emmanuel, Zeiser, Robert
Published 2013

Prdm6 Is Essential for Cardiovascular Development In Vivo

by Gewies, Andreas, Castineiras-Vilarino, Mercedes, Ferch, Uta, Jährling, Nina, Heinrich, Katja, Hoeckendorf, Ulrike, Przemeck, Gerhard K. H., Munding, Matthias, Groß, Olaf, Schroeder, Timm, Horsch, Marion, Karran, E. Loraine, Majid, Aneela, Antonowicz, Stefan, Beckers, Johannes, Hrabé de Angelis, Martin, Dodt, Hans-Ulrich, Peschel, Christian, Förster, Irmgard, Dyer, Martin J. S., Ruland, Jürgen
Published 2013

Pathogenic Fungi Regulate Immunity by Inducing Neutrophilic Myeloid-Derived Suppressor Cells

by Rieber, Nikolaus, Singh, Anurag, Öz, Hasan, Carevic, Melanie, Bouzani, Maria, Amich, Jorge, Ost, Michael, Ye, Zhiyong, Ballbach, Marlene, Schäfer, Iris, Mezger, Markus, Klimosch, Sascha N., Weber, Alexander N.R., Handgretinger, Rupert, Krappmann, Sven, Liese, Johannes, Engeholm, Maik, Schüle, Rebecca, Salih, Helmut Rainer, Marodi, Laszlo, Speckmann, Carsten, Grimbacher, Bodo, Ruland, Jürgen, Brown, Gordon D., Beilhack, Andreas, Loeffler, Juergen, Hartl, Dominik
Published 2015