The immune response in HPV+ oropharyngeal cancer

by King, Emma V, Ottensmeier, Christian H, Thomas, Gareth J
Published 2014

CD8+ T-cell cross-competition is governed by peptide–MHC class I stability

by Galea, Ian, Stasakova, Jana, Dunscombe, Melanie S, Ottensmeier, Christian H, Elliott, Tim, Thirdborough, Stephen M
Published 2012

Evaluation of immune infiltration in the colonic mucosa of patients with ipilimumab-related colitis

by Arriola, Edurne, Wheater, Matthew, Lopez, Maria Antonette, Thomas, Gareth, Ottensmeier, Christian
Published 2016

Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma

by Karydis, Ioannis, Chan, Pui Ying, Wheater, Matthew, Arriola, Edurne, Szlosarek, Peter W., Ottensmeier, Christian H.
Published 2016

Vaccination Expands Antigen-Specific CD4+ Memory T Cells and Mobilizes Bystander Central Memory T Cells

by Li Causi, Eleonora, Parikh, Suraj C., Chudley, Lindsey, Layfield, David M., Ottensmeier, Christian H., Stevenson, Freda K., Di Genova, Gianfranco
Published 2015

Harmonization of the intracellular cytokine staining assay

by Welters, Marij J. P., Gouttefangeas, Cécile, Ramwadhdoebe, Tamara H., Letsch, Anne, Ottensmeier, Christian H., Britten, Cedrik M., van der Burg, Sjoerd H.
Published 2012

Health related quality of life outcomes for unresectable stage III or IV melanoma patients receiving ipilimumab treatment

by Revicki, Dennis A, van den Eertwegh, Alfons JM, Lorigan, Paul, Lebbe, Celeste, Linette, Gerald, Ottensmeier, Christian H, Safikhani, Shima, Messina, Marianne, Hoos, Axel, Wagner, Samuel, Kotapati, Srividya
Published 2012

Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies

by Gao, Yifang, Rae, William, Ramakrishnan, Keseva Ananth, Barcenas-Morales, Gabriela, Döffinger, Rainer, Eren, Efrem, Faust, Saul N., Ottensmeier, Christian H., Williams, Anthony P.
Published 2016

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

by Mandruzzato, Susanna, Brandau, Sven, Britten, Cedrik M., Bronte, Vincenzo, Damuzzo, Vera, Gouttefangeas, Cécile, Maurer, Dominik, Ottensmeier, Christian, van der Burg, Sjoerd H., Welters, Marij J. P., Walter, Steffen
Published 2016

Plant Virus Particles Carrying Tumour Antigen Activate TLR7 and Induce High Levels of Protective Antibody

by Jobsri, Jantipa, Allen, Alex, Rajagopal, Deepa, Shipton, Michael, Kanyuka, Kostya, Lomonossoff, George P., Ottensmeier, Christian, Diebold, Sandra S., Stevenson, Freda K., Savelyeva, Natalia
Published 2015

Randomized Trial of Erlotinib Plus Whole-Brain Radiotherapy for NSCLC Patients With Multiple Brain Metastases

by Lee, Siow Ming, Lewanski, Conrad R., Counsell, Nicholas, Ottensmeier, Christian, Bates, Andrew, Patel, Nirali, Wadsworth, Christina, Ngai, Yenting, Hackshaw, Allan, Faivre-Finn, Corinne
Published 2014

A plant-expressed conjugate vaccine breaks CD4+ tolerance and induces potent immunity against metastatic Her2+ breast cancer

by Chotprakaikiat, Warayut, Allen, Alex, Bui-Minh, Duc, Harden, Elena, Jobsri, Jantipa, Cavallo, Federica, Gleba, Yuri, Stevenson, Freda K., Ottensmeier, Christian, Klimyuk, Victor, Savelyeva, Natalia
Published 2016

Targeting gp100 and TRP-2 with a DNA vaccine: incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical...

by Patel, Poulam M., Ottensmeier, Christian H., Mulatero, Clive, Lorigan, Paul, Plummer, Ruth, Pandha, Hardev S., Elsheikh, Somaia, Hadjimichael, Efthymios, Villasanti, Naty, Cunnell, Michelle, Metheringham, Rachael L., Brentville, Victoria A., Machado, Lee, Daniels, Ian, Gijon, Mohamed, Hannaman, Drew, Durrant, Lindy
Published 2018

Serum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols

by Filbert, Helene, Attig, Sebastian, Bidmon, Nicole, Renard, Bernhard Y., Janetzki, Sylvia, Sahin, Ugur, Welters, Marij J. P., Ottensmeier, Christian, van der Burg, Sjoerd H., Gouttefangeas, Cécile, Britten, Cedrik M.
Published 2012

The development of standard samples with a defined number of antigen-specific T cells to harmonize T cell assays: a proof-of-principle study

by Singh, Satwinder Kaur, Tummers, Bart, Schumacher, Ton N., Gomez, Raquel, Franken, Kees L. M. C., Verdegaal, Els M., Laske, Karoline, Gouttefangeas, Cécile, Ottensmeier, Christian, Welters, Marij J. P., Britten, Cedrik M., van der Burg, Sjoerd H.
Published 2012

DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8+ T-cell responses and increases PSA doubling time

by Chudley, Lindsey, McCann, Katy, Mander, Ann, Tjelle, Torunn, Campos-Perez, Juan, Godeseth, Rosemary, Creak, Antonia, Dobbyn, James, Johnson, Bernadette, Bass, Paul, Heath, Catherine, Kerr, Paul, Mathiesen, Iacob, Dearnaley, David, Stevenson, Freda, Ottensmeier, Christian
Published 2012

Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

by Arriola, Edurne, Wheater, Matthew, Galea, Ian, Cross, Nadia, Maishman, Tom, Hamid, Debbie, Stanton, Louise, Cave, Judith, Geldart, Tom, Mulatero, Clive, Potter, Vannessa, Danson, Sarah, Woll, Pennella J., Griffiths, Richard, Nolan, Luke, Ottensmeier, Christian
Published 2016

Idiotypic DNA vaccination for the treatment of multiple myeloma: safety and immunogenicity in a phase I clinical study

by McCann, Katy J., Godeseth, Rosemary, Chudley, Lindsey, Mander, Ann, Di Genova, Gianfranco, Lloyd-Evans, Paul, Kerr, Jonathan P., Malykh, Vladimir B., Jenner, Matthew W., Orchard, Kim H., Stevenson, Freda K., Ottensmeier, Christian H.
Published 2015

TG4010 immunotherapy plus chemotherapy as first-line treatment of advanced non small cell lung cancer (NSCLC): Phase IIb results of the TIME trial

by Nemunaitis, John, Papai, Zsolt, Léna, Hervé, Losonczy, Gyorgy, Forget, Frederic, Chouaid, Christos, Szczesna, Alexandra, Gervais, Radj, Ottensmeier, Christian H, Beck, Joseph, Kazarnowicz, Andrzej, Westeel, Virginie, Debieuvre, Didier, Madroszyk, Anne, Felip, Enriqueta, Limacher, Jean Marc, Quoix, Elisabeth
Published 2015

Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients

by S. Ahmad, Saif, Qian, Wendi, Ellis, Sarah, Mason, Elaine, Khattak, Muhammad A., Gupta, Avinash, Shaw, Heather, Quinton, Amy, Kovarikova, Jarmila, Thillai, Kiruthikah, Rao, Ankit, Board, Ruth, Nobes, Jenny, Dalgleish, Angus, Grumett, Simon, Maraveyas, Anthony, Danson, Sarah, Talbot, Toby, Harries, Mark, Marples, Maria, Plummer, Ruth, Kumar, Satish, Nathan, Paul, Middleton, Mark R., Larkin, James, Lorigan, Paul, Wheater, Matthew, Ottensmeier, Christian H., Corrie, Pippa G.
Published 2015