Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?

by Plummer, Ruth
Published 2011

Phase 1 dose-escalation study of the PARP inhibitor CEP-9722 as monotherapy or in combination with temozolomide in patients with solid tumors

by Plummer, Ruth, Stephens, Peter, Aissat-Daudigny, Louiza, Cambois, Anne, Moachon, Gilbert, Brown, Peter D., Campone, Mario
Published 2014

Targeting the DNA Double Strand Break Repair Machinery in Prostate Cancer

by Shaheen, Fadhel S., Znojek, Pawel, Fisher, Ann, Webster, Martin, Plummer, Ruth, Gaughan, Luke, Smith, Graeme C. M., Leung, Hing Y., Curtin, Nicola J., Robson, Craig N.
Published 2011

A Phase I study of pazopanib in combination with gemcitabine in patients with advanced solid tumors

by Plummer, Ruth, Madi, Ayman, Jeffels, Melinda, Richly, Heike, Nokay, Bahar, Rubin, Stephen, Ball, Howard A., Weller, Steve, Botbyl, Jeffrey, Gibson, Diana M., Scheulen, Max E.
Published 2012

Targeting gp100 and TRP-2 with a DNA vaccine: incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical...

by Patel, Poulam M., Ottensmeier, Christian H., Mulatero, Clive, Lorigan, Paul, Plummer, Ruth, Pandha, Hardev S., Elsheikh, Somaia, Hadjimichael, Efthymios, Villasanti, Naty, Cunnell, Michelle, Metheringham, Rachael L., Brentville, Victoria A., Machado, Lee, Daniels, Ian, Gijon, Mohamed, Hannaman, Drew, Durrant, Lindy
Published 2018

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with...

by Drew, Yvette, Ledermann, Jonathan, Hall, Geoff, Rea, Daniel, Glasspool, Ros, Highley, Martin, Jayson, Gordon, Sludden, Julieann, Murray, James, Jamieson, David, Halford, Sarah, Acton, Gary, Backholer, Zoe, Mangano, Raffaella, Boddy, Alan, Curtin, Nicola, Plummer, Ruth
Published 2016

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with...

by Drew, Yvette, Ledermann, Jonathan, Hall, Geoff, Rea, Daniel, Glasspool, Ros, Highley, Martin, Jayson, Gordon, Sludden, Julieann, Murray, James, Jamieson, David, Halford, Sarah, Acton, Gary, Backholer, Zoe, Mangano, Raffaella, Boddy, Alan, Curtin, Nicola, Plummer, Ruth
Published 2016

Ipilimumab in the real world: the UK expanded access programme experience in previously treated advanced melanoma patients

by S. Ahmad, Saif, Qian, Wendi, Ellis, Sarah, Mason, Elaine, Khattak, Muhammad A., Gupta, Avinash, Shaw, Heather, Quinton, Amy, Kovarikova, Jarmila, Thillai, Kiruthikah, Rao, Ankit, Board, Ruth, Nobes, Jenny, Dalgleish, Angus, Grumett, Simon, Maraveyas, Anthony, Danson, Sarah, Talbot, Toby, Harries, Mark, Marples, Maria, Plummer, Ruth, Kumar, Satish, Nathan, Paul, Middleton, Mark R., Larkin, James, Lorigan, Paul, Wheater, Matthew, Ottensmeier, Christian H., Corrie, Pippa G.
Published 2015