Immune-related response criteria

The immune-related response criteria (irRC) is a set of published rules that define when tumors in cancer patients improve ("respond"), stay the same ("stabilize"), or worsen ("progress") during treatment, where the compound being evaluated is an immuno-oncology drug. Immuno-oncology, part of the broader field of cancer immunotherapy, involves agents which harness the body's own immune system to fight cancer. Traditionally, patient responses to new cancer treatments have been evaluated using two sets of criteria, the WHO criteria and the response evaluation criteria in solid tumors (RECIST). The immune-related response criteria, first published in 2009, arose out of observations that immuno-oncology drugs would fail in clinical trials that measured responses using the WHO or RECIST Criteria, because these criteria could not account for the time gap in many patients between initial treatment and the apparent action of the immune system to reduce the tumor burden. Provided by Wikipedia
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by Fox, Bernard A, Schendel, Dolores J, Butterfield, Lisa H, Aamdal, Steinar, Allison, James P, Ascierto, Paolo Antonio, Atkins, Michael B, Bartunkova, Jirina, Bergmann, Lothar, Berinstein, Neil, Bonorino, Cristina C, Borden, Ernest, Bramson, Jonathan L, Britten, Cedrik M, Cao, Xuetao, Carson, William E, Chang, Alfred E, Characiejus, Dainius, Choudhury, A Raja, Coukos, George, de Gruijl, Tanja, Dillman, Robert O, Dolstra, Harry, Dranoff, Glenn, Durrant, Lindy G, Finke, James H, Galon, Jerome, Gollob, Jared A, Gouttefangeas, Cécile, Grizzi, Fabio, Guida, Michele, Håkansson, Leif, Hege, Kristen, Herberman, Ronald B, Hodi, F Stephen, Hoos, Axel, Huber, Christoph, Hwu, Patrick, Imai, Kohzoh, Jaffee, Elizabeth M, Janetzki, Sylvia, June, Carl H, Kalinski, Pawel, Kaufman, Howard L, Kawakami, Koji, Kawakami, Yutaka, Keilholtz, Ulrich, Khleif, Samir N, Kiessling, Rolf, Kotlan, Beatrix, Kroemer, Guido, Lapointe, Rejean, Levitsky, Hyam I, Lotze, Michael T, Maccalli, Cristina, Maio, Michele, Marschner, Jens-Peter, Mastrangelo, Michael J, Masucci, Giuseppe, Melero, Ignacio, Melief, Cornelius, Murphy, William J, Nelson, Brad, Nicolini, Andrea, Nishimura, Michael I, Odunsi, Kunle, Ohashi, Pamela S, O'Donnell-Tormey, Jill, Old, Lloyd J, Ottensmeier, Christian, Papamichail, Michael, Parmiani, Giorgio, Pawelec, Graham, Proietti, Enrico, Qin, Shukui, Rees, Robert, Ribas, Antoni, Ridolfi, Ruggero, Ritter, Gerd, Rivoltini, Licia, Romero, Pedro J, Salem, Mohamed L, Scheper, Rik J, Seliger, Barbara, Sharma, Padmanee, Shiku, Hiroshi, Singh-Jasuja, Harpreet, Song, Wenru, Straten, Per Thor, Tahara, Hideaki, Tian, Zhigang, van Der Burg, Sjoerd H, von Hoegen, Paul, Wang, Ena, Welters, Marij JP, Winter, Hauke, Withington, Tara, Wolchok, Jedd D, Xiao, Weihua, Zitvogel, Laurence, Zwierzina, Heinz, Marincola, Francesco M, Gajewski, Thomas F, Wigginton, Jon M, Disis, Mary L
Published 2011
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by Galluzzi, Lorenzo, Vacchelli, Erika, Pedro, José-Manuel Bravo-San, Buqué, Aitziber, Senovilla, Laura, Baracco, Elisa Elena, Bloy, Norma, Castoldi, Francesca, Abastado, Jean-Pierre, Agostinis, Patrizia, Apte, Ron N., Aranda, Fernando, Ayyoub, Maha, Beckhove, Philipp, Blay, Jean-Yves, Bracci, Laura, Caignard, Anne, Castelli, Chiara, Cavallo, Federica, Celis, Estaban, Cerundolo, Vincenzo, Clayton, Aled, Colombo, Mario P., Coussens, Lisa, Dhodapkar, Madhav V., Eggermont, Alexander M., Fearon, Douglas T., Fridman, Wolf H., Fučíková, Jitka, Gabrilovich, Dmitry I., Galon, Jérôme, Garg, Abhishek, Ghiringhelli, François, Giaccone, Giuseppe, Gilboa, Eli, Gnjatic, Sacha, Hoos, Axel, Hosmalin, Anne, Jäger, Dirk, Kalinski, Pawel, Kärre, Klas, Kepp, Oliver, Kiessling, Rolf, Kirkwood, John M., Klein, Eva, Knuth, Alexander, Lewis, Claire E., Liblau, Roland, Lotze, Michael T., Lugli, Enrico, Mach, Jean-Pierre, Mattei, Fabrizio, Mavilio, Domenico, Melero, Ignacio, Melief, Cornelis J., Mittendorf, Elizabeth A., Moretta, Lorenzo, Odunsi, Adekunke, Okada, Hideho, Palucka, Anna Karolina, Peter, Marcus E., Pienta, Kenneth J., Porgador, Angel, Prendergast, George C., Rabinovich, Gabriel A., Restifo, Nicholas P., Rizvi, Naiyer, Sautès-Fridman, Catherine, Schreiber, Hans, Seliger, Barbara, Shiku, Hiroshi, Silva-Santos, Bruno, Smyth, Mark J., Speiser, Daniel E., Spisek, Radek, Srivastava, Pramod K., Talmadge, James E., Tartour, Eric, Van Der Burg, Sjoerd H., Van Den Eynde, Benoît J., Vile, Richard, Wagner, Hermann, Weber, Jeffrey S., Whiteside, Theresa L., Wolchok, Jedd D., Zitvogel, Laurence, Zou, Weiping, Kroemer, Guido
Published 2014
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