Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase η for A/T

by Neuberger, Michael S., Rada, Cristina
Published 2007

The Immunoglobulin (Ig)α and Igβ Cytoplasmic Domains Are Independently Sufficient to Signal B Cell Maturation and Activation in Transgenic Mice

by Teh, Yih-Miin, Neuberger, Michael S.
Published 1997

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2 −/− ung −/− mice

by Xue, Kanmin, Rada, Cristina, Neuberger, Michael S.
Published 2006

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

by Uchimura, Yasuhiro, Barton, Lance F., Rada, Cristina, Neuberger, Michael S.
Published 2011

Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies

by Ehrenstein, Michael R., Cook, H. Terence, Neuberger, Michael S.
Published 2000

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung−/−Msh2−/− mice...

by Kemmerich, Kristin, Dingler, Felix A., Rada, Cristina, Neuberger, Michael S.
Published 2012

AID up-mutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity

by Wang, Meng, Yang, Zizhen, Rada, Cristina, Neuberger, Michael S.
Published 2009

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

by Dingler, Felix A., Kemmerich, Kristin, Neuberger, Michael S., Rada, Cristina
Published 2014

Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities

by Langlois, Marc-André, Beale, Rupert C. L., Conticello, Silvestro G., Neuberger, Michael S.
Published 2005

Deficiency in CD22, a B Cell–specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies

by O'Keefe, Theresa L., Williams, Gareth T., Batista, Facundo D., Neuberger, Michael S.
Published 1999

Somatic Hypermutation in the Absence of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-Pkcs) or Recombination-Activating Gene (Rag)1 Activity

by Bemark, Mats, Sale, Julian E., Kim, Hye-Jung, Berek, Claudia, Cosgrove, Ruth A., Neuberger, Michael S.
Published 2000

CTNNBL1 Is a Novel Nuclear Localization Sequence-binding Protein That Recognizes RNA-splicing Factors CDC5L and Prp31

by Ganesh, Karuna, Adam, Salome, Taylor, Benjamin, Simpson, Paul, Rada, Cristina, Neuberger, Michael
Published 2011

The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin

by Ellyard, Julia I, Benk, Amelie S, Taylor, Benjamin, Rada, Cristina, Neuberger, Michael S
Published 2011

Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice

by Chandra, Anita, van Maldegem, Febe, Andrews, Simon, Neuberger, Michael S., Rada, Cristina
Published 2013

Dependence of antibody gene diversification on uracil excision

by Di Noia, Javier M., Williams, Gareth T., Chan, Denice T.Y., Buerstedde, Jean-Marie, Baldwin, Geoff S., Neuberger, Michael S.
Published 2007

Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α☆

by Ganesh, Karuna, van Maldegem, Febe, Telerman, Stephanie B., Simpson, Paul, Johnson, Christopher M., Williams, Roger L., Neuberger, Michael S., Rada, Cristina
Published 2014

Carcinoid tumours of the lung and the ‘PEPPS’ approach: evaluation of preoperative bronchoscopic tumour debulking as preparation for subsequent parenchyma-sparing surgery

by Neuberger, Michael, Hapfelmeier, Alexander, Schmidt, Michael, Gesierich, Wolfgang, Reichenberger, Frank, Morresi-Hauf, Alicia, Hatz, Rudolf A, Lindner, Michael
Published 2015

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

by Taylor, Benjamin JM, Nik-Zainal, Serena, Wu, Yee Ling, Stebbings, Lucy A, Raine, Keiran, Campbell, Peter J, Rada, Cristina, Stratton, Michael R, Neuberger, Michael S
Published 2013

Cytomegalovirus containing TRP2 antigen provides protective immunity against the poorly immunogenic B16BL6-D5 melanoma

by Neuberger, Michael, Jensen, Shawn M, Xu, Guangwu, Smith, Tameka, Hu, Hong-Ming, Hill, Ann B, Bifulco, Carlo B, Fox, Bernard A
Published 2013

Multispectral imaging and objective assessment of immune-tumor interactions in non-small cell lung cancer

by Ballesteros-Merino, Carmen, Neuberger, Michael, Feng, Zipei, Huber, Rudolf Maria, Stump, Julia, Tufman, Amanda, Hatz, Rudolf, Linder, Michael, Sanborn, Rachel, Hussain, Sanaa, Handy, John R, Urba, Walter, Fox, Bernard, Bifulco, Carlo, Reu, Simone, Winter, Hauke
Published 2015