SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control

by Huynh, Frank K., Muoio, Deborah M., Hirschey, Matthew D.
Published 2015

Metabolomic analysis reveals decreased skeletal muscle amino acid content and altered fatty acid handling in obese humans

by Baker, Peter R., Boyle, Kristen E., Koves, Timothy R., Ilkayeva, Olga R., Muoio, Deborah M., Houmard, Joseph A., Friedman, Jacob E.
Published 2015

Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle

by Barrientos, Tomasa, Laothamatas, Indira, Koves, Timothy R., Soderblom, Erik J., Bryan, Miles, Moseley, M. Arthur, Muoio, Deborah M., Andrews, Nancy C.
Published 2015

Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

by Li, Lei O., Grevengoed, Trisha J., Paul, David S., Ilkayeva, Olga, Koves, Timothy R., Pascual, Florencia, Newgard, Christopher B., Muoio, Deborah M., Coleman, Rosalind A.
Published 2015

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

by Ussher, John R., Koves, Timothy R., Cadete, Virgilio J.J., Zhang, Liyan, Jaswal, Jagdip S., Swyrd, Suzanne J., Lopaschuk, David G., Proctor, Spencer D., Keung, Wendy, Muoio, Deborah M., Lopaschuk, Gary D.
Published 2010

SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase

by Laurent, Gaëlle, German, Natalie J, Saha, Asish K, de Boer, Vincent CJ, Fischer, Frank, Boanca, Gina, Dephoure, Noah, Vaitheesvaran, Bhavapriya, Davies, Michael, Gygi, Steven P, Muoio, Deborah M, Kurland, Irwin J, Steegborn, Clemens, Ruderman, Neil B, Haigis, Marcia C
Published 2012

Metabolic Remodeling of Human Skeletal Myocytes by Cocultured Adipocytes Depends on the Lipolytic State of the System

by Kovalik, Jean-Paul, Slentz, Dorothy, Stevens, Robert D., Kraus, William E., Houmard, Joseph A., Nicoll, James B., Lea-Currie, Y. Renee, Everingham, Karen, Kien, C. Lawrence, Buehrer, Benjamin M., Muoio, Deborah M.
Published 2011

A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults

by Kien, C. Lawrence, Bunn, Janice Y., Poynter, Matthew E., Stevens, Robert, Bain, James, Ikayeva, Olga, Fukagawa, Naomi K., Champagne, Catherine M., Crain, Karen I., Koves, Timothy R., Muoio, Deborah M.
Published 2013

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

by Wong, Kari E., Mikus, Catherine R., Slentz, Dorothy H., Seiler, Sarah E., DeBalsi, Karen L., Ilkayeva, Olga R., Crain, Karen I., Kinter, Michael T., Kien, C. Lawrence, Stevens, Robert D., Muoio, Deborah M.
Published 2015

Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

by Kraus, William E., Muoio, Deborah M., Stevens, Robert, Craig, Damian, Bain, James R., Grass, Elizabeth, Haynes, Carol, Kwee, Lydia, Qin, Xuejun, Slentz, Dorothy H., Krupp, Deidre, Muehlbauer, Michael, Hauser, Elizabeth R., Gregory, Simon G., Newgard, Christopher B., Shah, Svati H.
Published 2015

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate

by Keenan, Melissa M., Liu, Beiyu, Tang, Xiaohu, Wu, Jianli, Cyr, Derek, Stevens, Robert D., Ilkayeva, Olga, Huang, Zhiqing, Tollini, Laura A., Murphy, Susan K., Lucas, Joseph, Muoio, Deborah M., Kim, So Young, Chi, Jen-Tsan
Published 2015

Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion

by Soni, Mufaddal S., Rabaglia, Mary E., Bhatnagar, Sushant, Shang, Jin, Ilkayeva, Olga, Mynatt, Randall, Zhou, Yun-Ping, Schadt, Eric E., Thornberry, Nancy A., Muoio, Deborah M., Keller, Mark P., Attie, Alan D.
Published 2014